Results 281 to 290 of about 441,826 (314)
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Characterizing the physical genome
Nature Genetics, 2002The genome of an organism is a dynamic physical entity, comprising genomic DNA bound to many different proteins and organized into chromosomes. A thorough characterization of the physical genome is relevant to our understanding of processes such as the regulation of gene expression, DNA replication and repair, recombination, chromosome segregation ...
Jonathan R, Pollack, Vishwanath R, Iyer
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Characterization of Allomyces genome
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1977Allomyces arbuscula DNA isolated from whole cells (bulk DNA) is composed of a major (alpha) and two minor components (beta & gamma) with buoyant densities in neutral CsCl corresponding to 1.721, 1.710 and 1.702 g/cm3, respectively. The DNA obtained from purified nuclei contains alpha component only.
M, Ojha, H, Turler, G, Turian
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Genomic and antigenic characterization of avipoxviruses
Virus Research, 1988A permanent cell line of avian origin, QT-35, was used for the propagation of avipoxvirus isolates, including juncopox, pigeon pox, and field and vaccine strains of fowlpox viruses. The genomes of these avipoxvirus isolates were compared by restriction enzyme analysis using BamHI and HindIII endonuclease digestion and subsequent agarose gel ...
W M, Schnitzlein +2 more
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Characterization of the Drugged Human Genome
Pharmacogenomics, 2007Human drug targets are a part of our genome of special relevance to human disease. However, the number and nature of drug target genes has not yet been conclusively assessed. We analyzed involvement in biochemical functions, biological processes and pathways, with chromosome, cellular and tissue distribution of the 392 human drug targets collected in ...
Martin, Lauss +3 more
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Characterization of indels in poxvirus genomes
Virus Genes, 2010By comparing sets of variola virus (VARV) genomes and sets of vaccinia virus (VACV) genomes, it was found that the insertion and deletion of small pieces of DNA (3-25 nucleotides) were common events among these poxviruses. Insertion events were characterized by the creation of tandem direct repeats, whereas the deletion events generally took place ...
Danielle, Coulson, Chris, Upton
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Genetic and Genomic Characterization of Soles
2019Genome architecture of soles has been intensively explored in the last years, particularly with the arrival of Next Generation Sequencing (NGS) techniques. Hence, a large amount of transcriptomic and genomic data has been generated facilitating the identification of molecular markers and the development of expression tools required to decipher the ...
Manchado, Manuel +4 more
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Characterization of the genome of Phycomyces blakesleeanus
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975DNA of Phycomyces blakesleeanus was extracted from whole mycelia and from nuclear and mitochondrial organelle fractions obtained from sporangiophores. DNA from all three sources exhibits one symmetrical band at p equals 1.688 g/ml in CsCl buoyant density gradients. Reassociation data are consistent with kinetic division of the DNA into three components:
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Characterization of the nuclear genome of pearl millet
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1979The nuclear genome of pearl millet has been characterized with respect to its size, buoyant density in CsCl equilibrium density gradients, melting temperature, reassociation kinetics and sequence organization. The genome size is 0.22 pg. The mol percent G + C of the DNA is calculated from the buoyant density and the melting temperature to be 44.9 and ...
C F, Wimpee, J R, Rawson
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Characterization of the genome of the murine papovavirus K
Journal of Virology, 1979The DNA genome of the murine papovavirus K virus (KV) was characterized and compared with the genome of polyoma virus. A physical map of the KV genome was constructed by analysis of the size of DNA fragments generated by sequential cleavage with combinations of restriction endonucleases.
M F, Law, K K, Takemoto, P M, Howley
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