Results 61 to 70 of about 821,530 (308)

Biosynthesis and enzymology of the Caenorhabditis elegans cuticle: identification and characterization of a novel serine protease inhibitor. [PDF]

open access: yes, 2006
The nematode Caenorhabditis elegans represents an excellent model in which to examine nematode gene expression and function. A completed genome, straightforward transgenesis, available mutants and practical genome-wide RNAi approaches provide an ...
Andrew J. Birnie   +42 more
core   +1 more source

Characterizing Phage Genomes for Therapeutic Applications [PDF]

open access: yesViruses, 2018
Multi-drug resistance is increasing at alarming rates. The efficacy of phage therapy, treating bacterial infections with bacteriophages alone or in combination with traditional antibiotics, has been demonstrated in emergency cases in the United States and in other countries, however remains to be approved for wide-spread use in the US.
Casandra Philipson   +9 more
openaire   +3 more sources

Comparative Molecular Characterization of Novel and Known Piscine Toti-Like Viruses

open access: yesViruses, 2021
Totiviridae is a virus family well known to infect uni-cellular organisms like fungi and protozoa. In more recent years, viruses characterized as toti-like viruses, have been found in primarily arthropods, but also a couple in planarians and piscine ...
Liv Sandlund   +6 more
doaj   +1 more source

Genomic Characterization of Differentiated Thyroid Carcinoma [PDF]

open access: yesEndocrinology and Metabolism, 2019
Since the release of The Cancer Genome Atlas study of papillary thyroid carcinoma (PTC) in 2014, additional genomic studies of differentiated thyroid carcinoma (DTC) using massively-parallel sequencing (MPS) have been published. Recent advances in MPS technology have started to provide important insights into the molecular pathogenesis of DTC.
Young Shin Song, Young Joo Park
openaire   +3 more sources

Genomic Characterization of Probiotic Purple Nonsulfur Bacteria Cereibacter sphaeroides Strains S3W10 and SS15: Implications for Enhanced Shrimp Aquaculture

open access: yesLife
Cereibacter sphaeroides strains S3W10 and SS15, isolated from shrimp ponds, exhibit potential probiotic benefits for aquaculture. In this study, the genomic features of S3W10 and SS15 were thoroughly characterized to evaluate their probiotic properties ...
Chollachai Klaysubun   +8 more
doaj   +1 more source

Genomic and Phenotypic Characterization of Campylobacter fetus subsp. venerealis Strains

open access: yesMicroorganisms, 2021
The pathogenesis mechanisms of Campylobacter fetus subsp. venerealis (Cfv), the etiologic agent of Bovine Genital Campylobacteriosis remain elusive. This study evaluated the virulence potential and biovar characteristics of Cfv isolates (n = 13) by PCR ...
Marta F. Silva   +6 more
doaj   +1 more source

Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia. [PDF]

open access: yes, 2012
BackgroundEndophenotypes are quantitative, laboratory-based measures representing intermediate links in the pathways between genetic variation and the clinical expression of a disorder.
Braff, David L   +8 more
core   +2 more sources

Antimicrobial resistance and genomic characterization of Escherichia coli from pigs and chickens in Zhejiang, China

open access: yesFrontiers in Microbiology, 2022
Escherichia coli is considered an opportunistic pathogen and an indicator for antimicrobial resistance (AMR) monitoring. Despite many reports on its AMR monitoring, studies based on genome-based analysis of AMR genes are still insufficient.
Wei Zhou   +17 more
doaj   +1 more source

Weighted genomic distance can hardly impose a bound on the proportion of transpositions

open access: yes, 2010
Genomic distance between two genomes, i.e., the smallest number of genome rearrangements required to transform one genome into the other, is often used as a measure of evolutionary closeness of the genomes in comparative genomics studies.
Alekseyev, Max A., Jiang, Shuai
core   +1 more source

The antibody loci of the domestic goat (Capra hircus) [PDF]

open access: yes, 2018
The domestic goat (Capra hircus) is an important ruminant species both as a source of antibody-based reagents for research and biomedical applications and as an economically important animal for agriculture, particularly for developing nations that ...
Bickhart, Derek M.   +4 more
core   +1 more source

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