Results 71 to 80 of about 821,530 (308)

Characterization of Ebolavirus regulatory genomic regions [PDF]

Virus Research, 2009
For filoviruses, such as Ebolavirus and the closely related Marburgvirus, transcriptional regulation is poorly understood. The open reading frames (ORFs) that encode the viral proteins are separated by regulatory regions composed of the 3' nontranslated region (NTR) of the upstream gene, highly conserved transcription stop and start signals, and the 5 ...
Gabriele, Neumann, Shinji, Watanabe, Yoshihiro, Kawaoka   +2 more
openaire   +2 more sources

The Plasmid Mobilome of the Model Plant-Symbiont Sinorhizobium meliloti: Coming up with New Questions and Answers [PDF]

, 2014
Rhizobia are Gram-negative Alpha- andBetaproteobacteria living in the underground that have theability to associate with legumes for the establishment ofnitrogen-fixing symbioses.Sinorhizobium melilotiinparticular—the symbiont ofMedicago,Melilotus ...
Lagares, Antonio, Pistorio, Mariano, Sanjuán Pinilla, Juan   +2 more
core   +2 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

micRocounter: Microsatellite Characterization in Genome Assemblies [PDF]

G3 Genes|Genomes|Genetics, 2019
Abstract Microsatellites are repetitive DNA sequences usually found in non-coding regions of the genome. Their quantification and analysis have applications in fields from population genetics to evolutionary biology. As genome assemblies become commonplace, the need for software that can facilitate analyses has never been greater.
Johnathan Lo, Michelle M Jonika, Heath Blackmon   +2 more
openaire   +3 more sources

Genomic Characterization of the Istrian Shorthaired Hound [PDF]

Animals, 2020
Istrian shorthaired hound is an old indigenous Croatian dog breed with historical traces of its origin, which date back to the 14th century. Due to its intelligence and great hunting abilities, it is considered an excellent hunting dog. Despite its ancient origin, there is no data on genetic diversity, population structure, and degree of inbreeding ...
Ivona Djurkin Kušec, Ivica Bošković, Minja Zorc, Kristina Gvozdanović, Dubravko Škorput, Peter Dovč, Goran Kušec   +6 more
openaire   +3 more sources

Comprehensive Genomics Investigation of Neboviruses Reveals Distinct Codon Usage Patterns and Host Specificity

Microorganisms
Neboviruses (NeVs) from the Caliciviridae family have been linked to enteric diseases in bovines and have been detected worldwide. As viruses rely entirely on the cellular machinery of the host for replication, their ability to thrive in a specific host ...
Rahul Kaushik, Naveen Kumar, Pragya Yadav, Shubhankar Sircar, Anita Shete-Aich, Ankur Singh, Shailly Tomar, Thomas Launey, Yashpal Singh Malik   +8 more
doaj   +1 more source

Characterization of Pax3 and Sox10 Transgenic Xenopus Laevis Embryos as Tools to Study Neural Crest Development [PDF]

, 2018
The neural crest is a multipotent population of cells that originates a variety of cell types. Many animal models are used to study neural crest induction, migration and differentiation, with amphibians and birds being the most widely used systems.
Alkobtawi, Mansour, Barriga, Elias H., Kerney, Ryan R., Mayor, Roberto, Monsoro-Burq, Anne-Helene, Moreno, Mauricio, Ray, Heather, Saint-Jeannet, Jean-Pierre   +7 more
core   +2 more sources

Genomic characterization in dilated cardiomyopathy

Revista Portuguesa de Cardiologia, 2019
© 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.
openaire   +4 more sources

Characterizing the morbid genome of ciliopathies [PDF]

Genome Biology, 2016
Ciliopathies are clinically diverse disorders of the primary cilium. Remarkable progress has been made in understanding the molecular basis of these genetically heterogeneous conditions; however, our knowledge of their morbid genome, pleiotropy, and variable expressivity remains incomplete.We applied genomic approaches on a large patient cohort of 371 ...
Ranad Shaheen, Katarzyna Szymańska, Basudha Basu, Nisha Patel, Nour Ewida, Eissa Faqeih, Amal Al Hashem, Nada Derar, Hadeel Alsharif, Mohammed A. Aldahmesh, Anas M. Alazami, Mais Hashem, Niema Ibrahim, Firdous Abdulwahab, Rawda Sonbul, Hisham Alkuraya, Maha Alnemer, Saeed Al Tala, Muneera Al-Husain, Heba Morsy, Mohammed Zain Seidahmed, Neama Meriki, Mohammed Al‐Owain, Saad AlShahwan, Brahim Tabarki, Mustafa A. Salih, Tariq Faquih, Mohamed El-Kalioby, Marius Ueffing, Karsten Boldt, Clare V. Logan, David Parry, Nada Al‐Tassan, Dorota Monies, André Mégarbané, Mohamed Abouelhoda, Anason Halees, Colin A. Johnson, Fowzan S. Alkuraya   +38 more
openaire   +2 more sources

Disaggregating non-volatile memory for throughput-oriented genomics workloads [PDF]

, 2018
Massive exploitation of next-generation sequencing technologies requires dealing with both: huge amounts of data and complex bioinformatics pipelines.
A Kawalia, H Li, MJ Puckelwartz, P Medvedev, R Li, V Moncunill   +5 more
core   +1 more source