Results 21 to 30 of about 421,782 (313)
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations [PDF]
Nature, 2016 Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of ...Mallick, S., Li, H., Lipson, M., Mathieson, I., Gymrek, M., Racimo, F., Zhao, M.Y., Chennagiri, N., Nordenfelt, S., Tandon, A., Skoglund, P., Lazaridis, I., Sankararaman, S., Fu, Q.M., Rohland, N., Renaud, G., Erlich, Y., Willems, T., Gallo, C., Spence, J.P., Song, Y.S., Poletti, G., Balloux, F., Driem, G. van, Knijff, P. de, Romero, I.G., Jha, A.R., Behar, D.M., Bravi, C.M., Capelli, C., Hervig, T., Moreno-Estrada, A., Posukh, O.L., Balanovska, E., Balanovsky, O., Karachanak-Yankova, S., Sahakyan, H., Toncheva, D., Yepiskoposyan, L., Tyler-Smith, C., Xue, Y., Abdullah, M.S., Ruiz-Linares, A., Beall, C.M., Rienzo, A. di, Jeong, C., Starikovskaya, E.B., Metspalu, E., Parik, J., Villems, R., Henn, B.M., Hodoglugil, U., Mahley, R., Sajantila, A., Stamatoyannopoulos, G., Wee, J.T.S., Khusainova, R., Khusnutdinova, E., Litvinov, S., Ayodo, G., Comas, D., Hammer, M.F., Kivisild, T., Klitz, W., Winkler, C.A., Labuda, D., Bamshad, M., Jorde, L.B., Tishkoff, S.A., Watkins, W.S., Metspalu, M., Dryomov, S., Sukernik, R., Singh, L., Thangaraj, K., Paabo, S., Kelso, J., Patterson, N., Reich, D. +78 moreopenaire +11 more sourcesGenomic variations define divergence of water/wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes [PDF]
, 2011 Although the major food-borne pathogen Campylobacter jejuni has been isolated from diverse animal, human and environmental sources, our knowledge of genomic diversity in C.French, Nigel P., Hinds, Jason, Hall, N, Hepworth, Philip J., Gould, Katherine A., Gould, Katherine A, Adam A. Witney, Ashelford, Kevin E., Birtles, Richard J, Philip J. Hepworth, Kevin E. Ashelford, Nicola J. Williams, Winstanley, Craig, Howard Leatherbarrow, Wren, BW, Witney, AA, Birtles, Richard J., Neil Hall, French, Nigel P, Katherine A. Gould, Witney, Adam A., Hinds, J, Williams, Nicola J., Jason Hinds, Nigel P. French, Winstanley, C, Leatherbarrow, Howard, Paul Wigley, Williams, Nicola J, Birtles, RJ, Wren, Brendan W, Craig Winstanley, Mendonca, C, Mendonca, Chriselle, Hepworth, Philip J, Gould, KA, Wigley, Paul, Brendan W. Wren, Wren, Brendan W., Nick Dorrell, French, NP, Wigley, P, Hepworth, PJ, Leatherbarrow, H, Williams, NJ, Witney, Adam A, Dorrell, Nick, Chriselle Mendonca, Hall, Neil, Dorrell, N, Ashelford, KE, Ashelford, Kevin E, Richard J. Birtles +52 morecore +1 more sourceGenomic Diversity of Burkholderia pseudomallei Isolates, Colombia
Emerging Infectious Diseases, 2021 We report an analysis of the genomic diversity of isolates of Burkholderia pseudomallei, the cause of melioidosis, recovered in Colombia from routine surveillance during 2016–2017. B.Carolina Duarte, Franco Montufar, Jaime Moreno, Dora Sánchez, Jose Yesid Rodríguez, Alfredo G. Torres, Soraya Morales, Adriana Bautista, Mónica G. Huertas, Julia N. Myers, Christopher A. Gulvik, Mindy G. Elrod, David D. Blaney, Jay E. Gee +13 moredoaj +1 more sourceThe Pitfalls of Genomic Data Diversity
Hastings Center Report, 2023 AbstractBiomedical research recruitment today focuses on including participants representative of global genetic variation—rightfully so. But ethnographic attention to practices of inclusion highlights how this agenda often transforms into “predatory inclusion,” simplistic pushes to get Black and brown people into genomic databases.Jabloner, Anna, Walker, Alexisopenaire +2 more sourcesGenomic diversity of the human intestinal parasite Entamoeba histolytica. [PDF]
, 2012 BACKGROUND: Entamoeba histolytica is a significant cause of disease worldwide. However, little is known about the genetic diversity of the parasite.Tannich, Egbert, Egbert Tannich, Koldkjaer, Pia, Kay, Suzanne, Iris Bruchhaus, C Graham Clark, Bruchhaus, Iris, Steve Paterson, Neil Hall, Gareth D Weedall, Weedall, Gareth D, Clark, C Graham, Hall, Neil, Pia Koldkjaer, Suzanne Kay, Paterson, Steve +15 morecore +1 more sourcePhage diversity, genomics and phylogeny [PDF]
Nature Reviews Microbiology, 2020 Recent advances in viral metagenomics have enabled the rapid discovery of an unprecedented catalogue of phages in numerous environments, from the human gut to the deep ocean. Although these advances have expanded our understanding of phage genomic diversity, they also revealed that we have only scratched the surface in the discovery of novel viruses ...Moïra B. Dion, Frank Oechslin, Sylvain Moineau +2 moreopenaire +2 more sourcesIndependent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region [PDF]
, 2012 Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functional Gagneux, Sebastian, Michael Koehrsen (185361), Bonnie B Plikaytis, van Helden, Paul D., Sisk, P., Stolte, Christian, Hung, D., Jared White, Paul D. van Helden (33594), Gey van Pittius, Nicolass C., Brian Weiner, Gagneux, Sebastien, Gomez James, Bruce Birren, Sisk, Peter, Hung, Deborah, Sloutsky Alexander, White, Jared, Robert M. Warren (185350), Nicolass C. Gey van Pittius (185359), Deborah Hung (185364), Birren, Bruce, Warren, Robert M., Peter Sisk (185362), Galagan, J., van Helden, P. D., Robert M Warren, Nicolass C Gey van Pittius, Bonnie B. Plikaytis (185356), Paul D van Helden, Megan Murray (63415), Birren Bruce, Plikaytis, Bonnie B., Weiner, Brian, Koehrsen Michael, Galagan, James E., Victor Thomas C., Warren, R. M., Sloutsky, A., Bruce Birren (18146), Weiner Brian, Birren, B., Van Pittius, Nicolaas C. Gey, Christian Stolte, Stolte Christian, Gomez, J., Posey James E., Plikaytis Bonnie B., Gagneux, S., Peter Sisk, Brian Weiner (164963), James Gomez (185343), Posey, J. E., Thomas C Victor, Michael Koehrsen, Jared White (185363), Galagan James, Weiner, B., James Gomez, Warren Robert M., Gagneux Sebastien, James Galagan (185365), Murray, M., White Jared, Gey van Pittius, N. C., Galagan, James, James E Posey, White, J., Sloutsky, Alexander, Hung Deborah, Alexander Sloutsky, Stolte, C., James Galagan, Gomez, James, Deborah Hung, Sebastien Gagneux (149824), Plikaytis, B. B., Posey, James E., Koehrsen, M., Warren, Rob, van Helden Paul D., Alexander Sloutsky (185354), Sisk Peter, Sebastien Gagneux, Murray Megan, James E. Posey (155073), Murray, Megan, Megan Murray, Koehrsen, Michael, Victor, Thomas C., Victor, T. C., Christian Stolte (2869), Gey van Pittius Nicolass C., Thomas C. Victor (185348) +93 morecore +1 more sourcePresence of a loner strain maintains cooperation and diversity in well-mixed bacterial communities [PDF]
, 2016 Cooperation and diversity abound in nature despite cooperators risking exploitation from defectors and superior competitors displacing weaker ones. Understanding the persistence of cooperation and diversity is therefore a major problem for evolutionary ...Inglis, R. Fredrik, Kümmerli, Rolf, Biernaskie, Jay M., Inglis, R Fredrik, Inglis, Robert, Biernaskie, Jay, Gardner, Andy +6 morecore +1 more source