Results 1 to 10 of about 131,595 (265)

Beyond microbial core genomic epidemiology: towards pan genomic epidemiology

The Lancet Microbe, 2022
Santiago Castillo-Ramírez
doaj   +3 more sources

Characterizing <i>Staphylococcus aureus</i> genomic epidemiology with multilevel genome typing. [PDF]

mSystems
ABSTRACT Staphylococcus aureus is a major source of both hospital- and community-acquired infections worldwide. Advances in whole-genome sequencing (WGS) technologies have recently generated large volumes of S. aureus
Payne M, Cheney L, Kaur S, McKew G, Lan R.   +4 more
europepmc   +2 more sources

Genomic epidemiology of <i>Histoplasma</i> in Africa. [PDF]

mBio
ABSTRACT Histoplasmosis, the disease caused by thermally dimorphic fungi in the genus Histoplasma , is usually associated with pulmonary involvement in healthy individuals and a disseminated syndrome in immunocompromised patients. Among African patients, lung disease is less
Mapengo RE, Maphanga TG, Jofre GI, Rader JA, Turissini DA, Birkhead M, Kwabia SA, Sepúlveda VE, Buitrago MJ, Teixeira MdM, Barker BM, Alanio A, Sturny-Leclère A, Garcia-Hermoso D, Govender NP, Matute DR.   +15 more
europepmc   +3 more sources

Bacterial genomic epidemiology with mixed samples [PDF]

Microbial Genomics, 2021
Genomic epidemiology is a tool for tracing transmission of pathogens based on whole-genome sequencing. We introduce the mGEMS pipeline for genomic epidemiology with plate sweeps representing mixed samples of a target pathogen, opening the possibility to sequence all colonies on selective plates with a single DNA extraction and sequencing step.
Mäklin, Tommi, Kallonen, Teemu, Alanko, Jarno, Samuelsen, Ørjan, Hegstad, Kristin, Mäkinen, Veli, Corander, Jukka, Heinz, Eva, Honkela, Antti   +8 more
openaire   +5 more sources

Genomics and epidemiological surveillance [PDF]

Nature Reviews Microbiology, 2020
This month’s Genome Watch highlights how genomic surveillance can provide important information for identifying and tracking emerging pathogens such as SARS-CoV-2.
Lo, Stephanie W., Jamrozy, Dorota
openaire   +2 more sources

Bacterial Genomics and Epidemiology

Microorganisms, 2023
Innovative technologies for Whole-Genome Sequencing (WGS) help to improve our understanding of the epidemiology and pathogenesis of bacterial infectious diseases and are becoming affordable for most microbiological laboratories [...]
Javier Garaizar, Lorena Laorden
openaire   +4 more sources

Global Distribution of mcr Gene Variants in 214K Metagenomic Samples

mSystems, 2022
Since the initial discovery of a mobilized colistin resistance gene (mcr-1), several other variants have been reported, some of which might have circulated a while beforehand.
Hannah-Marie Martiny, Patrick Munk, Christian Brinch, Judit Szarvas, Frank M. Aarestrup, Thomas Nordahl Petersen   +5 more
doaj   +1 more source

Benzodiazepine-related dementia risks and protopathic biases revealed by multiple-kernel learning with electronic medical records

Digital Health, 2023
Objectives To simultaneously estimate how the risk of incident dementia nonlinearly varies with the administration period and cumulative dose of benzodiazepines, the duration of disorders with an indication for benzodiazepines, and other potential ...
Takashi Hayakawa, Takuya Nagashima, Hayato Akimoto, Kimino Minagawa, Yasuo Takahashi, Satoshi Asai   +5 more
doaj   +1 more source

A Peek into the Plasmidome of Global Sewage

mSystems, 2021
This is, to the best of our knowledge, the first study to investigate plasmidomes at a global scale using long read sequencing from complex untreated domestic sewage.
Philipp Kirstahler, Frederik Teudt, Saria Otani, Frank M. Aarestrup, Sünje Johanna Pamp   +4 more
doaj   +1 more source

Genomic epidemiology on the move

Nature Reviews Microbiology, 2022
This Genome Watch article explores how portable sequencing technology is reshaping the field of genomic epidemiology.
Catherine N. Wilson, Patrick Musicha, Mathew A. Beale   +2 more
openaire   +2 more sources