Results 11 to 20 of about 21,875 (202)

Genomic consequences of intensive inbreeding in miniature inbred pigs

BMC Genomics
Background Inbreeding, a central theme in evolutionary and conservation biology, is a crucial practice in breeding to stabilize and enhance the specific traits or to establish inbred lines.
Hong-Man Chen, Heng Zhao, Qun-Yao Zhu, Chen Yan, Ya-Qi Liu, Si Si, Muhammad Ameen Jamal, Kai-Xiang Xu, De-Ling Jiao, Min-Juan Lv, Wen Wang, Hong-Ye Zhao, Lei Chen, Ming-Shan Wang, Hong-Jiang Wei   +14 more
doaj   +3 more sources

Genomic analysis of the inbreeding load for body weight, carcass and reproductive traits in the Rubia Gallega beef cattle population [PDF]

Genetics Selection Evolution
Background Inbreeding, resulting from mating between relatives, leads to inbreeding depression, which can be traced back to hidden ancestral inbreeding loads.
Carlos Hervás-Rivero, David López-Carbonell, Manuel Sánchez-Díaz, Luis Varona   +3 more
doaj   +2 more sources

Genomic partitioning of inbreeding depression in humans [PDF]

The American Journal of Human Genetics, 2021
Across species, offspring of related individuals often exhibit significant reduction in fitness-related traits, known as inbreeding depression (ID), yet the genetic and molecular basis for ID remains elusive. Here, we develop a method to quantify enrichment of ID within specific genomic annotations and apply it to human data.
Loic Yengo, Jian Yang, Matthew C. Keller, Michael E. Goddard, Naomi R. Wray, Peter M. Visscher   +5 more
openaire   +4 more sources

Runs of homozygosity reveal population dynamics and selection across global cattle [PDF]

Journal of Animal Science and Biotechnology
Background Cattle have undergone complex evolutionary trajectories shaped by domestication, migration, and selection. Although runs of homozygosity (ROH) are a ubiquitous genomic feature, their full potential to decipher the evolutionary history and ...
Jun Ma, Xinxia Liu, Xue Gao, Dawei Wei, Zijing Zhang, Abdullah Muhammad, Ningbo Chen, Xiaoting Xia, Yun Ma, Eryao Wang, Xian Liu, Chuzhao Lei, Yu Jiang, Yongzhen Huang   +13 more
doaj   +2 more sources

Genomic and fitness consequences of inbreeding in an endangered carnivore [PDF]

Molecular Ecology, 2021
AbstractReduced fitness through genetic drift and inbreeding is a major threat to small and isolated populations. Although previous studies have generally used genetically verified pedigrees to document effects of inbreeding and gene flow, these often fail to capture the whole inbreeding history of the species.
Malin Hasselgren, Nicolas Dussex, Johanna von Seth, Anders Angerbjörn, Remi‐André Olsen, Love Dalén, Karin Norén   +6 more
openaire   +4 more sources

Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat. [PDF]

Animals (Basel)
Cashmere goats are valuable genetic resources which are famous worldwide for their high-quality fiber. Runs of homozygosity (ROHs) have been identified as an efficient tool to assess inbreeding level and identify related genes under selection. However, there is limited research on ROHs in cashmere goats.
Zhao Q, Huang C, Chen Q, Su Y, Zhang Y, Wang R, Su R, Xu H, Liu S, Ma Y, Zhao Q, Ye S.   +11 more
europepmc   +4 more sources

Trends in genetic diversity and the effect of inbreeding in American Angus cattle under genomic selection

Genetics Selection Evolution, 2021
Background While the adoption of genomic evaluations in livestock has increased genetic gain rates, its effects on genetic diversity and accumulation of inbreeding have raised concerns in cattle populations.
Emmanuel A. Lozada-Soto, Christian Maltecca, Duc Lu, Stephen Miller, John B. Cole, Francesco Tiezzi   +5 more
doaj   +1 more source

Genomic consequences of isolation and inbreeding in an island dingo population

Genome Biology and Evolution, 2023
ABSTRACT Dingoes come from an ancient canid lineage that originated in East Asia around 8000-11,000 years BP. As Australia’s largest terrestrial predator, dingoes play an important ecological role. A small, protected population exists on a world heritage listed offshore island, K’gari (formerly Fraser Island).
Ana V Leon-Apodaca, Manoharan Kumar, Andres del Castillo, Gabriel C Conroy, Robert W Lamont, Steven Ogbourne, Kylie M Cairns, Liz Borburgh, Linda Behrendorff, Sankar Subramanian, Zachary A Szpiech   +10 more
openaire   +3 more sources

Genomic signatures of inbreeding in a critically endangered parrot, the kākāpō [PDF]

G3 Genes|Genomes|Genetics, 2021
Abstract Events of inbreeding are inevitable in critically endangered species. Reduced population sizes and unique life-history traits can increase the severity of inbreeding, leading to declines in fitness and increased risk of extinction. Here, we investigate levels of inbreeding in a critically endangered flightless parrot, the kākāpō
Yasmin Foster, Ludovic Dutoit, Stefanie Grosser, Nicolas Dussex, Brodie J Foster, Ken G Dodds, Rudiger Brauning, Tracey Van Stijn, Fiona Robertson, John C McEwan, Jeanne M E Jacobs, Bruce C Robertson   +11 more
openaire   +3 more sources

Genomics advances the study of inbreeding depression in the wild [PDF]

Evolutionary Applications, 2016
AbstractInbreeding depression (reduced fitness of individuals with related parents) has long been a major focus of ecology, evolution, and conservation biology. Despite decades of research, we still have a limited understanding of the strength, underlying genetic mechanisms, and demographic consequences of inbreeding depression in the wild.
Kardos, Marty, Taylor, Helen R., Ellegren, Hans, Luikart, Gordon, Allendorf, Fred W.   +4 more
openaire   +3 more sources