Results 81 to 90 of about 22,116 (210)

Homozygosity and risk of childhood death due to invasive bacterial disease. [PDF]

, 2009
BACKGROUND: Genetic heterozygosity is increasingly being shown to be a key predictor of fitness in natural populations, both through inbreeding depression, inbred individuals having low heterozygosity, and also through chance linkage between a marker and

core   +1 more source

The scale of population structure in Arabidopsis thaliana [PDF]

, 2010
The population structure of an organism reflects its evolutionary history and influences its evolutionary trajectory. It constrains the combination of genetic diversity and reveals patterns of past gene flow.
A Rafalski, A Storfer, Alexander Platt, Alison E. Anastasio, Andrew Hudson, BF Voight, BS Weir, CD Bustamante, Detlef Weigel, Diane Byers, Eric B. Holub, ES Buckler, Fabrice Roux, FX Pico, G Guillot, G Guillot, J Marchini, JB Beck, JF Wilkins, JF Wilkins, John Novembre, Jon Ågren, Joy Bergelson, Justin O. Borevitz, Kathleen Donohue, LJ Heyer, LL Knowles, Luz Rivero, M Nordborg, Magnus Nordborg, Matthew Horton, Megan Dunning, N Warthmann, NH Barton, Ni Wayan Mulyati, Norman Warthmann, Oliver Bossdorf, Olivier Loudet, P Lewis, Randy Scholl, RM Kliman, S Atwell, S Wright, SL O'Kane, T Maruyama, T Mitchell-Olds, T Sasaki, Valérie Le Corre, Y Li, Yan Li, Yu S. Huang   +50 more
core   +7 more sources

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

Integrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng, Yihua Wang, Yiyuan Zhang, Lei Gao, Lili Wu, Shuping Wang, Yiyang Gao, Wanlu Shi, Kaixin Lu, Rong Deng, Junting Li, Jing Han, Xiaohui Lu, Yujie Liu, Xiaojiao Tang, Yunxia Zhang, Guoyin Li, Li Huang, Mingsheng Yang, Xiaoyan Li   +19 more
wiley   +1 more source

Runs of homozygosity in a selected cattle population with extremely inbred bulls: Descriptive and functional analyses revealed highly variable patterns. [PDF]

PLoS ONE, 2018
The analysis of runs of homozygosity (ROH), using high throughput genomic data, has become a valuable and frequently used methodology to characterize the genomic and inbreeding variation of livestock and wildlife animal populations.
Daniel Goszczynski, Antonio Molina, Ester Terán, Hernán Morales-Durand, Pablo Ross, Hao Cheng, Guillermo Giovambattista, Sebastián Demyda-Peyrás   +7 more
doaj   +1 more source

Microhaplotype Methods Enable Relationship Inference in a Bottlenecked Mammalian Species

Animal Conservation, EarlyView.
Northern elephant seals (Mirounga angustirostris) are among the most genetically depauperate mammals in the world. A near‐total population bottleneck in the 19th century, coupled with the breeding system of extreme polygyny, has challenged efforts to estimate individual reproductive success with genetic methods.
Keith M. Hernandez, Anthony J. Clemento, Juliette E. Linossier, Daniel E. Crocker, Daniel P. Costa, Colleen Reichmuth, John Carlos Garza   +6 more
wiley   +1 more source

Genomic characterization of autozygosity and recent inbreeding trends in all major breeds of US dairy cattle

Journal of Dairy Science, 2022
: Maintaining a genetically diverse dairy cattle population is critical to preserving adaptability to future breeding goals and avoiding declines in fitness.
Emmanuel A. Lozada-Soto, Francesco Tiezzi, Jicai Jiang, John B. Cole, Paul M. VanRaden, Christian Maltecca   +5 more
doaj   +1 more source

A genome-wide study of Hardy–Weinberg equilibrium with next generation sequence data [PDF]

, 2017
Statistical tests for Hardy–Weinberg equilibrium have been an important tool for detecting genotyping errors in the past, and remain important in the quality control of next generation sequence data.
AM Veerappa, Bruce Weir, BS Weir, Deepti Jain, DL Hartl, G Benson, I Gomes, J Graffelman, J Graffelman, J Graffelman, JA Bailey, JA Traherne, Jan Graffelman, JE Wigginton, JF Crow, JS Beckmann, L Crooks, L Hosking, R Nielsen, RV Rohlfs, SM Leal, TH Emigh, The MHC sequencing consortium, YY Teo   +23 more
core   +3 more sources

Nest Survival Models and Genomics Illuminate Hybridisation Attempts, Guiding Culturally Informed Management to Recover a Critically Endangered Seabird

Animal Conservation, EarlyView.
Long‐term monitoring has revealed hybridisation attempts between the Critically Endangered Kuaka Whenua Hou (KWH, Pelecanoides whenuahouensis) and the abundant Kuaka (P. urinatrix). Here we use modelling based on population monitoring data in tandem with genomic data to investigate these attempts and the risk they pose to KWH recovery.
N. J. Forsdick, T. R. Buckley, T. Davis, I. Debski, J. H. Fischer   +4 more
wiley   +1 more source

Genome-Wide Scan for Runs of Homozygosity Identifies Candidate Genes in Three Pig Breeds

Animals, 2019
Runs of homozygosity (ROH) are contiguous homozygous genotype segments in the genome that are present in an individual since the identical haplotypes are inherited from each parent.
Rui Xie, Liangyu Shi, Jiaxin Liu, Tianyu Deng, Lixian Wang, Yang Liu, Fuping Zhao   +6 more
doaj   +1 more source

Next-generation metrics for monitoring genetic erosion within populations of conservation concern [PDF]

, 2017
This work was conducted as a part of the Next-generation Genetic Monitoring Working Group at the National Institute for Mathematical and Biological Synthesis, sponsored by the National Science Foundation through NSF Award #DBI-1300426, with additional ...
Bruford, M. W., Carroll, E. L., DeWoody, J. A., Leroy, G., Strand, A., Waits, L., Wang, J.   +6 more
core   +3 more sources