Results 1 to 10 of about 662,435 (169)

Endometriosis: candidate genes [PDF]

Human Reproduction Update, 2001
Endometriosis is generally regarded as a benign disease but it does exhibit some characteristics reminiscent of malignancy. This raises the possibility that, like malignant diseases, the development of endometriosis may involve the acquisition of somatic genetic alterations in genes that regulate cell growth and differentiation.
I G, Campbell, E J, Thomas
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Identification of a Candidate Gene for Astigmatism [PDF]

Investigative Opthalmology & Visual Science, 2013
Astigmatism is a common refractive error that reduces vision, where the curvature and refractive power of the cornea in one meridian are less than those of the perpendicular axis. It is a complex trait likely to be influenced by both genetic and environmental factors.
Lopes, Margarida C., Hysi, Pirro G., Verhoeven, Virginie J. M., Macgregor, Stuart, Hewitt, Alex W., Montgomery, Grant W., Cumberland, Phillippa, Vingerling, Johannes R., Young, Terri L., van Duijn, Cornelia M., Oostra, Ben, Uitterlinden, Andre G., Rahi, Jugnoo S., Mackey, David A., Klaver, Caroline C. W., Andrew, Toby, Hammond, Christopher J.   +16 more
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Candidate gene prioritization with Endeavour [PDF]

Nucleic Acids Research, 2016
Genomic studies and high-throughput experiments often produce large lists of candidate genes among which only a few are truly relevant to the disease, phenotype, or biological process of interest. Gene prioritization tackles this problem by ranking candidate genes by profiling candidates across multiple genomic data sources and ...
Léon-Charles Tranchevent, Amin Ardeshirdavani, Sarah ElShal, Daniel Alcaide, Jan Aerts, Didier Auboeuf, Yves Moreau   +6 more
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Probing the Gene eXpression Database for candidate genes [PDF]

European Journal of Human Genetics, 1999
We report on a strategy for the identification of candidate genes for multiple malformation syndromes using expression data available in public databases. The basis for this pilot study was the assumption that, for a multiple malformation syndrome, the expression pattern of the causative gene should at least cover the organs or tissues affected by the ...
Steensel, M.A.M. van, Celli, J., Bokhoven, J.H.L.M. van, Brunner, H.G.   +3 more
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The Important Candidate Genes in Goats - A Review

Walailak Journal of Science and Technology, 2011
A total of 271 candidate genes have been detected in goats. However, comprehensive investigations have been carried out on the polymorphism of some genes, involved in the control of economic traits.
China SUPAKORN
doaj   +1 more source

The Brazilian contribution to Attention-Deficit/Hyperactivity Disorder molecular genetics in children and adolescents

Genetics and Molecular Biology, 2012
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common psychiatric condition of children worldwide. This disorder is defined by a combination of symptoms of inattention and hyperactivity/impulsivity.
Júlia Pasqualini Genro, Tatiana Roman, Luis Augusto Rohde, Mara Helena Hutz   +3 more
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STK25 Is a Candidate Gene for Pseudopseudohypoparathyroidism

Genomics, 2001
We determined the chromosomal location of the mouse gene Stk25, encoding a member of the Ste20/PAK family of serine/threonine kinases, by interspecific backcross analysis. We mapped Stk25 to the central region of mouse chromosome 1 linked to Chrng (formerly Acrg) and En1.
Davids, M S, Crawford, E, Weremowicz, S, Morton, C C; id_orcid 0000-0003-2198-6756, Copeland, N G, Gilbert, D J, Jenkins, N A, Phelan, M C, Comb, M J, Melnick, M B   +9 more
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A Meta-Analysis Including Pre-selected Sequence Variants Associated With Seven Traits in Three French Dairy Cattle Populations

Frontiers in Genetics, 2018
A within-breed genome-wide association study (GWAS) is useful when identifying the QTL that segregates in a breed. However, an across-breed meta-analysis can be used to increase the power of identification and precise localization of QTL that segregate ...
Andrew G. Marete, Andrew G. Marete, Bernt Guldbrandtsen, Mogens S. Lund, Sébastien Fritz, Sébastien Fritz, Goutam Sahana, Didier Boichard   +7 more
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Search for Associations of FSHR, INHA, INHAB, PRL, TNP2 and SPEF2 Genes Polymorphisms with Semen Quality in Russian Holstein Bulls (Pilot Study)

Animals, 2021
The aim of the study was to search for new mutations in the previously studied gene loci of follicle-stimulating hormone receptor (FSHR), inhibin α (INHA), inhibin β A (INHAB), prolactin (PRL), transition protein 2 (TNP2), and sperm flagella 2 (SPEF2) by
Elena Nikitkina, Anna Krutikova, Artem Musidray, Kirill Plemyashov   +3 more
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Microarray analyses to identify differentially expressed genes for assessing meat quality in swine

Italian Journal of Animal Science, 2010
In order to identify candidate genes and molecular mechanisms that influence meat quality and production in pigs, microarray experiments were carried out to find differences in gene expression levels between two pools of six individuals, constituting the
G. Pagnacco, P. Mariani, A. Stella, C. Gorni, I. Iacuaniello, B. Castiglioni   +5 more
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