Results 21 to 30 of about 662,534 (268)

Is Mortalin a Candidate Gene for T1DM ?

Autoimmunity, 2004
Mortalin has been found to be up-regulated by 2D-protein gel analysis in isolated rodent islets exposed to cytokines. In islets from two rat strains with different sensitivity to the toxic effects of cytokines we observed a significant difference in IL-1beta mediated mortalin expression.
Jesper, Johannesen, Angeles, Pie, Allan Ertmann, Karlsen, Zenia Marian, Larsen, Allan, Jensen, Henrik, Vissing, Ole Peter, Kristiansen, Flemming, Pociot, Jørn, Nerup   +8 more
openaire   +2 more sources

Evaluating historical candidate genes for schizophrenia [PDF]

Molecular Psychiatry, 2015
Prior to the genome-wide association era, candidate gene studies were a major approach in schizophrenia genetics. In this invited review, we consider the current status of 25 historical candidate genes for schizophrenia (e.g., COMT, DISC1, DTNBP1, and NRG1).
Farrell, M. S., Werge, T., Sklar, P., Owen, M. J., Ophoff, R. A., O'Donovan, M. C., Corvin, A., Cichon, S., Sullivan, P. F.   +8 more
openaire   +5 more sources

The FAGenomicH project: towards a whole candidate gene approach to identify markers associated with fatness and production traits in pigs and investigate the pig as a model for human obesity

Italian Journal of Animal Science, 2010
Fatness in pigs is a complex trait for which a large number of genes are expected to be involved. Genetics of human obesity could take advantages from genetic information coming from the pig and vice versa.
Vincenzo Russo, Rita Casadio, Giovanni Romeo, Manuela Vargiolu, Elena Bonora, Daniela Giovanna Calò, Giuliano Galimberti, Lucia Tognazzi, Camilla Speroni, Emilio Scotti, Michela Colombo, Raffaele Fronza, Luca Fontanesi   +12 more
doaj   +1 more source

Expression of VINV1, SCB1 and SCS1 genes in the seed coats of contrasting soybean seeds1

Revista Ciência Agronômica
The seed coat is vital for the proper development of soybean seeds and also, after their physiological maturity, for providing protection against various biotic and abiotic factors.
Carlos André Bahry, Paulo Dejalma Zimmer   +1 more
doaj   +1 more source

Heritability and candidate genes for endometriosis

Reproductive BioMedicine Online, 2003
Endometriosis is inherited in polygenic/multifactorial fashion, with recurrence risks of 5-7% for first-degree relatives. The current task is to determine the number and location of causative genes. This review initially supports the basis for polygenic/multifactorial inheritance and then outlines genome-wide strategies for identifying causative genes.
Joe Leigh, Simpson, Farideh, Bischoff
openaire   +2 more sources

Candidate genes in ocular dominance plasticity [PDF]

Frontiers in Neuroscience, 2012
Many studies have been devoted to the identification of genes involved in experience-dependent plasticity in the visual cortex. To discover new candidate genes, we have reexamined data from one such study on ocular dominance (OD) plasticity in recombinant inbred BXD mouse strains. We have correlated the level of plasticity with the gene expression data
Rietman, M.L., Sommeijer, J.-P., Levelt, C.N., Heimel, J.A., Brussaard, A.B., Borst, J.G.G., Elgersma, Y., Galjart, N., van der Horst, G.T., Pennartz, C.M., Smit, A.B., Spruijt, B.M., Verhage, M., de Zeeuw, C.I.   +13 more
openaire   +5 more sources

Identification of candidate genes affecting the tibia quality in Nonghua duck

Poultry Science
: The skeleton is a vital organ providing structural support in poultry. Weakness in bone structure can lead to deformities, osteoporosis, cage fatigue, and fractures, resulting in economic losses.
Yinjuan Lu, Bin Wei, Qinglan Yang, Xu Han, Xinxin He, Qiuyu Tao, Shuaixue Jiang, Mengru Xu, Yuan Bai, Tao Zhang, Lili Bai, Jiwei Hu, Hehe Liu, Liang Li   +13 more
doaj   +1 more source

Candidate Genes in thyroid disorders

Клиническая и экспериментальная тиреоидология, 2005
Hypothyroidism and hyperthyroidism are well known to be the main clinical features of thyroid pathology. Although a lot of mechanisms of these disorders exist, thyroid resection, radioiodine or drug (antithyroid or hormone replacement) therapy are still ...

doaj   +1 more source

Potential biomarkers in personality disorders: current state and future research

International Journal of Psychological Research, 2016
This review article presents the most appropriate strategies for examining the phenotype for personality disorders. At present there are many neurobiological and molecular studies that suggest a genetic predisposition to different traits representative ...
Manuela Valencia Piedrahita, Jorge Mauricio Cuartas Arias   +1 more
doaj   +3 more sources

Transcriptomic Characterization of Candidate Genes for Fusarium Resistance in Maize (Zea mays L.)

Pathogens
Fusarium diseases are among the most dangerous fungal diseases of plants. To date, there are no plant protectants that completely prevent fusariosis. Current breeding trends are therefore focused on increasing genetic resistance.
Aleksandra Sobiech, Agnieszka Tomkowiak, Tomasz Jamruszka, Tomasz Kosiada, Julia Spychała, Maciej Lenort, Jan Bocianowski   +6 more
doaj   +1 more source