Results 11 to 20 of about 33,220 (219)

Endometriosis: candidate genes [PDF]

Human Reproduction Update, 2001
Endometriosis is generally regarded as a benign disease but it does exhibit some characteristics reminiscent of malignancy. This raises the possibility that, like malignant diseases, the development of endometriosis may involve the acquisition of somatic genetic alterations in genes that regulate cell growth and differentiation.
I G, Campbell, E J, Thomas
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Identification of a Candidate Gene for Astigmatism [PDF]

Investigative Opthalmology & Visual Science, 2013
Astigmatism is a common refractive error that reduces vision, where the curvature and refractive power of the cornea in one meridian are less than those of the perpendicular axis. It is a complex trait likely to be influenced by both genetic and environmental factors.
Lopes, Margarida C., Hysi, Pirro G., Verhoeven, Virginie J. M., Macgregor, Stuart, Hewitt, Alex W., Montgomery, Grant W., Cumberland, Phillippa, Vingerling, Johannes R., Young, Terri L., van Duijn, Cornelia M., Oostra, Ben, Uitterlinden, Andre G., Rahi, Jugnoo S., Mackey, David A., Klaver, Caroline C. W., Andrew, Toby, Hammond, Christopher J.   +16 more
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Candidate gene prioritization with Endeavour [PDF]

Nucleic Acids Research, 2016
Genomic studies and high-throughput experiments often produce large lists of candidate genes among which only a few are truly relevant to the disease, phenotype, or biological process of interest. Gene prioritization tackles this problem by ranking candidate genes by profiling candidates across multiple genomic data sources and ...
Léon-Charles Tranchevent, Amin Ardeshirdavani, Sarah ElShal, Daniel Alcaide, Jan Aerts, Didier Auboeuf, Yves Moreau   +6 more
openaire   +3 more sources

Probing the Gene eXpression Database for candidate genes [PDF]

European Journal of Human Genetics, 1999
We report on a strategy for the identification of candidate genes for multiple malformation syndromes using expression data available in public databases. The basis for this pilot study was the assumption that, for a multiple malformation syndrome, the expression pattern of the causative gene should at least cover the organs or tissues affected by the ...
Steensel, M.A.M. van, Celli, J., Bokhoven, J.H.L.M. van, Brunner, H.G.   +3 more
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STK25 Is a Candidate Gene for Pseudopseudohypoparathyroidism

Genomics, 2001
We determined the chromosomal location of the mouse gene Stk25, encoding a member of the Ste20/PAK family of serine/threonine kinases, by interspecific backcross analysis. We mapped Stk25 to the central region of mouse chromosome 1 linked to Chrng (formerly Acrg) and En1.
Davids, M S, Crawford, E, Weremowicz, S, Morton, C C; id_orcid 0000-0003-2198-6756, Copeland, N G, Gilbert, D J, Jenkins, N A, Phelan, M C, Comb, M J, Melnick, M B   +9 more
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Candidate and non-candidate genes in behavior genetics

Current Opinion in Neurobiology, 2013
In this review we discuss recent developments in psychiatric genetics: on the one hand, studies using whole genome approaches (genome-wide association studies (GWAS) and exome sequencing) are coming close to finding genes and molecular variants that contribute to disease susceptibility; on the other candidate genes, such as the serotonin transporter ...
Flint, Jonathan, Munafò, Marcus R
openaire   +5 more sources

Genetic polymorphism of four candidate genes in dairy cattle of Kashmir, India

Indian Journal of Animal Sciences, 2021
Genetic information is necessary to devise strategic plans aimed to improve the genetic merit of dairy cattle. Exploration of quantitative, qualitative, and molecular genetics is important to improve dairy cattle performance.
RUKSANA SHAH, N A GANAI, S SHANAZ, F D SHEIKH, H M KHAN, NUSRAT N KHAN, AMBREEN HAMADANI, SAFEER ALAM   +7 more
doaj   +1 more source

Integrative Computational Approach Revealed Crucial Genes Associated With Different Stages of Diabetic Retinopathy

Frontiers in Genetics, 2020
The increased incidence of diabetic retinopathy (DR) and the legacy effect associated with it has raised a great concern toward the need to find early diagnostic and treatment strategies.
Nidhi Kumari, Nidhi Kumari, Nidhi Kumari, Aditi Karmakar, Aditi Karmakar, Aditi Karmakar, Saikat Chakrabarti, Saikat Chakrabarti, Saikat Chakrabarti, Senthil Kumar Ganesan, Senthil Kumar Ganesan, Senthil Kumar Ganesan   +11 more
doaj   +1 more source

Differentially expressed genes against Colletotrichum lindemuthiamum in a bean genotype carrying the Co-2 gene revealed by RNA-sequencing analysis

Frontiers in Plant Science, 2022
Anthracnose is responsible for large yield losses in common bean crops. RNA-sequencing was used to investigate the differentially expressed genes (DEGs) in response to race 38 of Colletotrichum lindemuthianum in two near-isogenic lines (A25 and A4804 ...
Maria Jurado, Ana Campa, Juan Jose Ferreira   +2 more
doaj   +1 more source

Identification of Genomic Regions Associated with Fusarium Wilt Resistance in Cowpea

Applied Sciences, 2022
Fusarium wilt (FW), caused by the soil-borne fungal pathogen Fusarium oxysporum f. sp. Tracheiphilum, is a serious threat to cowpea production worldwide. Understanding the genetic architecture of FW resistance is a prerequisite to combatting this disease
Junyang Dong, Yuqin Song, Baogen Wang, Xiaohua Wu, Ying Wang, Jian Wang, Zhongfu Lu, Yan Zhang, Guojing Li, Xinyi Wu, Huasen Wang   +10 more
doaj   +1 more source