Results 41 to 50 of about 662,534 (268)

Genome-Wide Association Study Provides Insights into Important Genes for Reproductive Traits in Nelore Cattle

open access: yesAnimals, 2021
The identification of genomic regions associated with reproductive traits as well as their biological processes allows a better understanding of the phenotypic variability of these traits.
Ana Paula Sbardella   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Whole-Genome Sequencing in Premature Coronary Artery Disease in South Asians: A Pilot Case–Control Study

open access: yesCardiogenetics
Background/Objectives: Coronary artery disease (CAD) remains the leading cause of mortality worldwide, with South Asia bearing a disproportionately high and rising burden, particularly at younger ages.
Iftikhar Ali Ch   +13 more
doaj   +1 more source

Identifying candidate genes involved in trichome formation on carrot stems by transcriptome profiling and resequencing

open access: yesJournal of Integrative Agriculture, 2022
Trichomes are specialized structures developed from epidermal cells and can protect plants against biotic and abiotic stresses. Trichomes cover carrots during the generative phase.
Zhe WU, Xuan YANG, Yu-xuan ZHAO, Li JIA
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Candidate genes of Waldenström’s macroglobulinemia: current evidence and research

open access: yesThe Application of Clinical Genetics, 2013
Giada Bianchi,1 Antonio Sacco,1 Shaji Kumar,2 Giuseppe Rossi,3 Irene Ghobrial,1 Aldo Roccaro11Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 2Division of Hematology, Mayo Clinic, Rochester, MN, USA ...
Bianchi G   +5 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Variability of some genes of the somatotropic axis in the Piemontese cattle breed

open access: yesItalian Journal of Animal Science, 2011
Growth hormone (GH) is a major participant in the control of several complex physiological processes, including growth and metabolism. The growth promoting aspects are generally mediated by the insulin-like growth factor 1 (IGF-1), produced primarily in ...
S. Sartore, L. Di Stasio
doaj   +1 more source

Polymorphisms in MyoD1, MyoG, MyF5, MyF6, and MSTN genes in Santa Inês sheep [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2019
: The objective of this work was to sequence the MyoD1, MyoG, MyF5, MyF6, and MSTN genes and to identify polymorphisms in Santa Inês sheep (Ovis aries).
Luis Paulo Batista Sousa Junior   +7 more
doaj   +1 more source

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