Results 291 to 300 of about 596,095 (346)

Towards a Library of Standard Operating Procedures (SOPs) for (meta)genomic annotation

, 2008
Nikos C. Kyrpides, Samuel V. Angiuoli, Guy Cochrane, Dawn Field, George M Garrity, Aaron Gussman, Chinnappa D. Kodira, William Klimke, Nikos C. Kyrpides, Ramana Madupu, Victor Markowitz, Tatiana Tatusova, Nick Thomson, Owen White   +13 more
openalex   +1 more source

A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow

Advanced Science, EarlyView.
The MoSMAR‐chip platform provides a high‐throughput and cost‐effective tool for identifying and characterizing antigen‐specific antibody‐secreting cells (ASCs) and memory B cells (MBCs) at the single‐cell level. The ASCs from coronavirus disease 2019 (COVID‐19) vaccine‐immunized mice were successfully analyzed, revealing diverse neutralizing antibodies
Tian Zhao, Yuqing Lei, Chang Liu, Dong Zhang, Kaiyi Li, Sisi Shan, Chenyu Li, Zimeng Wei, Yuhan Yang, Ting Zhang, Kai Sun, Haoran Sun, Linqi Zhang, Peng Liu   +13 more
wiley   +1 more source

Assessment of the variant prioritisation strategy for genomic newborn screening in the Generation Study

Kaplanis J, Deen D, Sivakumar P, de Almeida Gomes M, Puzriakova A, Leong I, Savage K, Aldam G, Skelton J, Quinn P, Parrish A, Baple E, To M, Stone K, Bick D, Pichini A, Scott R, Thomas E, Kasperaviciute D.   +18 more
europepmc   +1 more source

HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo. [PDF]

BMC Genomics
Chang TY, Waxman DJ.
europepmc   +1 more source

Rare event detection using error-corrected DNA and RNA sequencing [PDF]

, 2018
Druley, Todd E, Tong, R. Spencer, Wong, Wing H, Young, Andrew L   +3 more
core   +1 more source

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

Advanced Science, EarlyView.
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi, Yu Tian, Yu‐fan Wang, Yi‐ran Zhang, Ying Yin, Qing Tian, Lei Li, Bing‐xin Ma, Ximiao He, Li‐quan Zhou   +9 more
wiley   +1 more source

Genomes of Prochlorococcus, Synechococcus, bacteria, and viruses recovered from marine picocyanobacteria cultures based on Illumina and Qitan nanopore sequencing. [PDF]

Sci Data
Wu Q, Gao J, Sa B, Cong H, Deng W, Zhang Y, Zhong X, Zhang J, Wang L, Liu H, Yan Y, Zhang Y, Liu D, Yan W.   +13 more
europepmc   +1 more source

MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu, Feng Zhang, Jingpu Wang, Jian Zhang, Chenguang Li, Yang Lyu, Yiwen Wang, Rong Huang, Yang Gao, Hongbo Yang, Juying Qian, Wenwen Tang, Jiatian Cao, Junbo Ge   +13 more
wiley   +1 more source

De Novo Genome Assembly and Comparative Genome Analysis of the Novel Human Fungal Pathogen Trichosporon austroamericanum Type-Strain CBS 17435. [PDF]

Mycopathologia
Francisco EC, Desnos-Ollivier M, Gerrits van den Ende B, Hagen F.   +3 more
europepmc   +1 more source

In Vivo Reprogramming of Tissue‐Derived Extracellular Vesicles for Treating Chronic Tissue Injury Through Metabolic Engineering

Advanced Science, EarlyView.
Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao, Shuyun Liu, Yizhuo Wang, Peng Lou, Ke Lv, Tian Wu, Lan Li, Qianyi Wu, Jiaying Zhu, Yanrong Lu, Meihua Wan, Jingping Liu   +11 more
wiley   +1 more source