Results 261 to 270 of about 2,453,732 (306)

EasyGeSe - a resource for benchmarking genomic prediction methods. [PDF]

open access: yesBMC Genomics
Quesada-Traver C   +3 more
europepmc   +1 more source

Reliabilities in genomic prediction

open access: yes, 2015
Ma, Peipei   +2 more
openaire   +1 more source
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Fold Predictions for Bacterial Genomes

Journal of Structural Biology, 2001
Fold assignments for newly sequenced genomes belong to the most important and interesting applications of the booming field of protein structure prediction. We present a brief survey and a discussion of such assignments completed to date, using as an example several fold assignment projects for proteins from the Escherichia coli genome.
Krzysztof Pawłowski   +3 more
openaire   +2 more sources

Microbiome genomics for cancer prediction

Nature Cancer, 2020
Although cancer genomics is a powerful tool to understand cancer and develop diagnostic tools, the contribution of the microbiome in cancer diagnosis and clinical assessment is much less studied. Elinav, Greten and colleagues provide their respective views on how studying cancer metagenomes could facilitate identification, diagnosis and staging of ...
Adlung, Lorenz   +3 more
openaire   +2 more sources

The Genomic Approach to Growth Prediction

Hormone Research in Paediatrics, 2007
<i>Background:</i> A major objective when using recombinant human growth hormone (rhGH) in childhood is to attain the maximum sustained growth response that can be achieved in an individual child while avoiding adverse events and ensuring that biomarkers of response, such as insulin-like growth factor I (IGF-I), remain within acceptable ...
Clayton, P. E.; id_orcid 0000-0003-1225-4537   +1 more
openaire   +1 more source

Predictive Genomic Biomarkers

2010
Advances in the biological characterization of tumors has led to the design and development of anticancer agents targeting specific molecular alterations. The majority of these agents are designed to silence phosphorylation signals that are required for the development and maintenance of the cancer phenotype in specific tumor types.
Rakesh, Kumar, Rafael G, Amado
openaire   +2 more sources

[Prediction of transcription and genomic sequences].

Medecine sciences : M/S, 2004
Technological developments have enhanced DNA sequencing at genomic scale. On the basis of the resulting sequences, computational biologists now attempt to localise the most important functional regions, starting with genes, but also importantly the regulatory motifs and conditions controlling their expression.
Martin, David   +2 more
openaire   +3 more sources

Genomics and the prediction of xenobiotic toxicity

Toxicology, 2002
The systematic identification and functional analysis of human genes is revolutionizing the study of disease processes and the development and rational use of drugs. It increasingly enables medicine to make reliable assessments of the individual risk to acquire a particular disease, raises the number and specificity of drug targets and explains ...
Meyer UA, Gut J
openaire   +3 more sources

Predicting structures for genome proteins

Current Opinion in Structural Biology, 1999
Assigning three-dimensional protein folds to genome sequences is essential to understanding protein function. Although experimental three-dimensional structures are currently available for only a very small fraction of these sequences, computational fold assignment is able to assign folds to 20-30% of the sequences in various genomes.
D, Fischer, D, Eisenberg
openaire   +2 more sources

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