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Genomic selection: genome-wide prediction in plant improvement
Trends in Plant Science, 2014Association analysis is used to measure relations between markers and quantitative trait loci (QTL). Their estimation ignores genes with small effects that trigger underpinning quantitative traits. By contrast, genome-wide selection estimates marker effects across the whole genome on the target population based on a prediction model developed in the ...
Zeratsion Abera, Desta, Rodomiro, Ortiz
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Predicting disease using genomics
Nature, 2004Information from the human genome sequence will eventually alter many aspects of clinical practice. It will increase through our understanding of disease mechanisms, and guide the development of new drugs and therapeutic procedures. In the short term, however, knowledge of the genome will have a profound clinical impact on the diagnostic capability of ...
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Prediction of Genomic Functional Elements
Annual Review of Genomics and Human Genetics, 2006As the number of sequenced genomes increases, the ability to deduce genome function becomes increasingly salient. For many genome sequences, the only annotation that will be available for the foreseeable future will be based on computational predictions and comparisons with functional elements in related species.
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An Integrative Approach for Genomic Island Prediction in Prokaryotic Genomes
2011A genomic island (GI) is a segment of genomic sequence that is horizontally transferred from other genomes. The detection of genomic islands is extremely important to the medical research. Most of current computational approaches that use sequence composition to predict genomic islands have the problem of low prediction accuracy.
Han Wang +4 more
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Nature, 2013
Microbial cells make up the majority of cells in the human body, and most of these reside in the intestinal tract. Researchers have long recognized that some intestinal microorganisms are associated with health, but the beneficial impact of most of the gut's microbes on human metabolism has been discovered only relatively ...
de Vos, W.M., Nieuwdorp, M.
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Microbial cells make up the majority of cells in the human body, and most of these reside in the intestinal tract. Researchers have long recognized that some intestinal microorganisms are associated with health, but the beneficial impact of most of the gut's microbes on human metabolism has been discovered only relatively ...
de Vos, W.M., Nieuwdorp, M.
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DNNGP, a deep neural network-based method for genomic prediction using multi-omics data in plants
Molecular Plant, 2023Awais Rasheed +2 more
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Haplotype blocks for genomic prediction: a comparative evaluation in multiple crop datasets
Frontiers in Plant Science, 2023Sven E Weber +2 more
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GAPIT Version 3: Boosting Power and Accuracy for Genomic Association and Prediction
Genomics, Proteomics and Bioinformatics, 2021Jiabo Wang, Zhiwu Zhang
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Predicting the regulatory genome
Nature Reviews GeneticsSarthak Tiwari +2 more
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