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Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

, 2013
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 3/13/13Official website of the Connecticut Judicial Selection Commission ...

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GENOMIC SELECTION IN DAIRY CATTLE

, 2023
Genomska selekcija je postala rutinska metoda pri mlečnih pasmah govedi. Z uvedbo genomske selekcije generacijski interval vsaj prepolovimo, kljub manjši točnosti plemenskih vrednosti, se genetski napredek poveča.
Marhat, Dejan
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Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Signatures of positive selection after the introduction of genomic selection in the Finnish Ayrshire population

Journal of Dairy Science
: The Finnish Ayrshire (FAY) belongs to the Nordic Red breeds and is characterized by high milk yield, high milk components, good fertility, and functional conformation. The FAY breeding program is based on genomic selection.
Katri Sarviaho, Pekka Uimari, Katja Martikainen   +2 more
doaj   +1 more source

A global network for investigating the genomic epidemiology of malaria.

, 2008
Large-scale studies of genomic variation could assist efforts to eliminate malaria. But there are scientific, ethical and practical challenges to carrying out such studies in developing countries, where the burden of disease is greatest.
Malaria Genomic Epidemiology Network, Malaria Genomic Epidemiology
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Efficiency of Genomic Selection for Developing Superior Pure Lines

Agronomy
The objectives were to assess the efficacy of genomic selection in pure line breeding, using a simulated dataset, the significance of several factors, including model updating, selection intensity, early generation (F2) selection, dominance, and the ...
Jean Paulo Aparecido da Silva, José Marcelo Soriano Viana   +1 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Deep learning for genomic selection.

, 2023
One of the significant challenges in the world is to feed its population, as around 193 million people are facing severe hunger. The solution to this problem is to increase the quality and quantity of food while facing the challenge of decreasing or degrading agricultural land.
openaire   +1 more source