Results 181 to 190 of about 3,983,457 (419)

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Dynamic transcriptome profiling revealed a key gene ZmJMJ20 and pathways associated with cadmium stress in maize

Ecotoxicology and Environmental Safety
Cadmium (Cd) pollution in soil poses a global concern due to its serious impacts on human health and ecological security. In plants, tremendous efforts have been made to identify some key genes and pathways in Cd stress responses. However, studies on the
Shuai Yu, Jialun Zhu, Yanzhe Yin, Xiaoyu Zhang, Yuxin Dai, Yupeng Xing, Xipeng Cheng, Ao Zhang, Cong Li, Yanshu Zhu, Yanye Ruan, Xiaomei Dong, Jinjuan Fan   +12 more
doaj  

Purification of genomic sequences from bacteriophage libraries by recombination and selectionin vivo [PDF]

, 1983
Brian Seed
openalex   +1 more source

Invited review: Genomic selection in dairy cattle: progress and challenges.

Journal of Dairy Science, 2009
A new technology called genomic selection is revolutionizing dairy cattle breeding. Genomic selection refers to selection decisions based on genomic breeding values (GEBV).
B. Hayes, P. Bowman, A. Chamberlain, M. Goddard   +3 more
semanticscholar   +1 more source

Information-theoretic View of Sequence Organization in a Genome [PDF]

arXiv, 2010
Sequence organizations are viewed from two points: one is from informational redundancy or informational correlation (IC) and another is from k-mer frequency statistics. Two problems are investigated. The first is how the ICs exceed the fluctuation bound and the order emerges from fluctuation in a genome when the sequence length attains some critical ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA. [PDF]

, 1987
Constance Brinckerhoff, Peggy L. Ruby, Scott D. Austin, M E Fini, Hillary D. White   +4 more
openalex   +1 more source

Genetic mapping and genomic selection for maize stalk strength

BMC Plant Biology, 2019
Maize is one of the most important staple crops and is widely grown throughout the world. Stalk lodging can cause enormous yield losses in maize production.
Xiaogang Liu, Xiaojia Hu, Kun Li, Zhifang Liu, Yujin Wu, Hongwu Wang, Changling Huang   +6 more
semanticscholar   +1 more source

Eukaryotes evade information storage-replication rate trade-off with endosymbiont assistance leading to larger genomes [PDF]

arXiv
Genome length varies widely among organisms, from compact genomes of prokaryotes to vast and complex genomes of eukaryotes. In this study, we theoretically identify the evolutionary pressures that may have driven this divergence in genome length.
arxiv  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source