Results 241 to 250 of about 149,760 (296)

Genomic Surveillance Reveals Vaccine-Associated Shifts in Pediatric Invasive Streptococcus pneumoniae in Tunisia. [PDF]

Vaccines (Basel)
Mhimdi S, Meftah K, Deghmane AE, Chelbi Y, Bouafsoun A, Taha MK, Smaoui H.   +6 more
europepmc   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Living at genetic risk: The patient experience of Lynch syndrome

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome is a germline cancer predisposition syndrome caused by a variant in one of four genes. Lynch syndrome places individuals at significantly higher risk for a range of cancers, especially colorectal and endometrial. Depending on which gene is affected, the risk of ovarian, gastric, small bowel, pancreatic, biliary urothelial, brain,
Nicola Reents, Georgina Hoffmann, Kelly Kohut   +2 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Nationwide Genomic Surveillance of Human Respiratory Adenoviruses in 2023-2024: Evidence of Extensive Diversity and Recombination in Russia. [PDF]

Viruses
Yolshin ND, Ivanova AA, Perederiy AA, Amosova IV, Timoshicheva TA, Stolyarov KA, Danilenko DM, Lioznov DA, Komissarov AB.   +8 more
europepmc   +1 more source

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

International Journal of Cancer, EarlyView.
What's New? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille, Vivian Viallon, Laia Peruchet‐Noray, Quan Gan, N. Charlotte Onland‐Moret, Yvonne Koop, Anne Tjønneland, Nicola Patricia Bondonno, Verena Katzke, Rudolf Kaaks, Matthias B. Schulze, Catarina Schiborn, Calogero Saieva, Vittorio Simeon, Claudia Agnoli, Rosario Tumino, Fulvio Ricceri, Leila Luján‐Barroso, Maria‐José Sánchez, Conchi Moreno‐Iribas, Konstantinos K. Tsilidis, Marc J. Gunter, Adam Butterworth, Elio Riboli, Heinz Freisling, Pietro Ferrari   +25 more
wiley   +1 more source

Comparative genomic surveillance of carbapenem-resistant <i>Acinetobacter baumannii</i> in the Netherlands in 2015-2017 and 2022-2024. [PDF]

Microbiol Spectr
Allewijn MP, Witteveen S, Vendrik KEW, de Haan A, Landman F, Bos J, Lansu S, Wielders CCH, Schoffelen AF, de Greeff SC, Notermans DW, Hendrickx APA, Dutch CPE Surveillance Study Group.   +12 more
europepmc   +1 more source

Hospital-Based Genomic Surveillance of <i>Klebsiella pneumoniae</i>: Trends in Resistance and Infection. [PDF]

Biology (Basel)
Olund-Matos E, Franco-Duarte R, Santa-Cruz A, Nogueira M, Correia-Neves M, Lopes D, Silva RJ, Araújo MR, Araújo IM, Martins AF, Nogueira CM, Faustino A, Cunha PG, Soares P, Rito T.   +14 more
europepmc   +1 more source

Targeted Genomic Surveillance Unveils Genetic Variations Linked to Regional Malaria Drug Resistance Dynamics in India. [PDF]

Open Forum Infect Dis
Khilari A, Sharma S, Bajpai M, Viswan K A, Chaturvedi R, Mirdha BR, Rahi M, Sharma A, Shanmugam D.   +8 more
europepmc   +1 more source