Results 111 to 120 of about 2,064,173 (379)

Lipid Metabolism and Comparative Genomics [PDF]

, 2006
Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette, Melrose, John, O’Malley, Brendan, Pickersgill, Laura, Rougier, Jonathan, Tindall, Marcus   +5 more
core  

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

The Collaborative African Genomics Network (CAfGEN): Applying Genomic technologies to probe host factors important to the progression of HIV and HIV-tuberculosis infection in sub-Saharan Africa [version 2; peer review: 2 approved]

AAS Open Research, 2018
Background: Here, we describe how the Collaborative African Genomics Network (CAfGEN) of the Human Heredity and Health in Africa (H3Africa) consortium is using genomics to probe host genetic factors important to the progression of HIV and HIV ...
Gerald Mboowa, Savannah Mwesigwa, Eric Katagirya, Gaone Retshabile, Busisiwe C. Mlotshwa, Lesedi Williams, Adeodata Kekitiinwa, David Kateete, Eddie Wampande, Misaki Wayengera, Betty Nsangi Kintu, Grace P. Kisitu, Samuel Kyobe, Chester W. Brown, Neil A. Hanchard, Graeme Mardon, Moses Joloba, Gabriel Anabwani, Ed Pettitt, Masego Tsimako-Johnstone, Ishmael Kasvosve, Koketso Maplanka, Sununguko W. Mpoloka, Makhosazana Hlatshwayo, Mogomotsi Matshaba   +24 more
doaj   +1 more source

Colonial Legacies, Postcolonial Biologies: Gender and the Promises of Biotechnology [PDF]

, 2015
Three decades of work in the feminist studies of science and technology have shaped our evolving understandings of the relationships between sex, gender, and biotechnology.
Subramaniam, Banu
core   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Building International Genomics Collaboration for Global Health Security

Frontiers in Public Health, 2015
Genome science and technologies are transforming life sciences globally in many ways, and becoming a highly desirable area for international collaboration to strengthen global health.
Helen H Cui, Tracy eErkkila, Patrick S G Chain, Momchilo eVuyisich   +3 more
doaj   +1 more source

The genome incorporated: constructing biodigital identity [PDF]

, 2010
The Genome Incorporated examines the proliferation of human genomics across contemporary media cultures. It explores questions about what it means for a technoscience to thoroughly saturate everyday life, and places the interrogation of the science/media
O'Riordan, Kate
core   +1 more source

4D, N = 1 Supersymmetry Genomics (I)

, 2009
Presented in this paper the nature of the supersymmetrical representation theory behind 4D, N = 1 theories, as described by component fields, is investigated using the tools of Adinkras and Garden Algebras.
A. Galperin, A. Galperin, B. Zwiebach, Boanne MacGregor, C.F. Doran ., C.F. Doran ., C.F. Doran ., C.F. Doran ., D. Freedman, D.Z. Freedman, E. Ivanov, James Gonzales, James Parker, Luke Wassink, M.G. Faux, Ruben Polo-Sherk, S. James Gates, S.J. Gates Jr., S.J. Gates Jr., S.J. Gates Jr., Vincent G.J Rodgers   +20 more
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The Ectocarpus Genome and Brown Algal Genomics

, 2012
Brown algae are important organisms both because of their key ecological roles in coastal ecosystems and because of the remarkable biological features that they have acquired during their unusual evolutionary history. The recent sequencing of the complete genome of the filamentous brown alga Ectocarpus has provided unprecedented access to the molecular
Colin Brownlee, Betsy A. Read, Hiroshi Kawai, Stefan A. Rensing, Sylvie Doulbeau, Patrick Wincker, Bank Beszteri, Bank Beszteri, Florian Maumus, Chris Bowler, Martina Strittmatter, John H. Bothwell, John H. Bothwell, John H. Bothwell, Taizo Motomura, Véronique Anthouard, Pascal J. Lopez, Thierry Tonon, Thierry Tonon, Martin Lohr, Erwan Corre, Carolyn A. Napoli, Catherine Leblanc, Catherine Leblanc, Olivier Godfroy, Olivier Godfroy, Takahiro Yamagishi, Claire Jubin, Corinne Da Silva, Alok Arun, Alok Arun, Hadi Quesneville, Simon M. Dittami, Simon M. Dittami, Julie Poulain, Akira F. Peters, Akira F. Peters, Eric Bonnet, Eric Bonnet, Julia Morales, Julia Morales, Grigoris D. Amoutzias, Grigoris D. Amoutzias, Hervé Moreau, Philippe Potin, Philippe Potin, Remy Luthringer, Remy Luthringer, James W. Tregear, Cindy Martens, Daniel Lang, Claire M. M. Gachon, Gurvan Michel, Gurvan Michel, J. Mark Cock, J. Mark Cock, Garry Farnham, Jonathan H. Badger, Svenja Heesch, Svenja Heesch, Sophia Ahmed, Sophia Ahmed, Pierre Rouzé, Ga Youn Cho, Ga Youn Cho, Marek Eliáš, Laurence Dartevelle, Laurence Dartevelle, Peter von Dassow, Patrice Lerouge, Nicolas Macaisne, Nicolas Macaisne, Yves Van de Peer, David R. Nelson, Carl J. Carrano, Ludovic Delage, Ludovic Delage, Frithjof C. Küpper, Frithjof C. Küpper, François Artiguenave, Delphine Scornet, Delphine Scornet, Andrés Ritter, Andrés Ritter, Andrés Ritter, Manoj P. Samanta, Bénédicte Charrier, Bénédicte Charrier, Kamel Jabbari, Chikako Nagasato, Jean-Marc Aury, Klaus Valentin, Bernard Kloareg, Bernard Kloareg, Pi Nyvall-Collén, Pi Nyvall-Collén, Gaelle Samson, Catherine Boyen, Catherine Boyen, Gildas Le Corguillé, Bernhard Gschloessl, Bernhard Gschloessl, Diego Miranda-Saavedra, Kenny Billiau, Nicolas Delaroque, Jonas Collén, Jonas Collén, Andrew E. Allen, Susana M. Coelho, Susana M. Coelho, Declan C. Schroeder, Béatrice Segurens, Aude Le Bail, Aude Le Bail, Kei Kimura, Lieven Sterck, Sylvie Rousvoal, Sylvie Rousvoal, Cyril Pommier   +118 more
openaire   +4 more sources