Results 101 to 110 of about 821,457 (264)
Multi-criteria assessment of ethical aspects in fresh tomato systems: Plant genomics technology innovation and food policy uses [PDF]
Product assessment for imperceptible characteristics like environmental impact, healthfulness, naturalness, and fairness is a helpful tool in product innovation and for enhancing socially responsible conduct.
Michalopoulos, T. +3 more
core
A summary report of the 8th annual International Workshop on Environmental Genomics (IWEG)
Centre for Environmental Genomics Applications, CEGA
core +1 more source
Gosling Designer: a Platform to Democratize Construction and Sharing of Genomics Data Visualization Tools [preprint] [PDF]
This article is a preprint. Preprints are preliminary reports of work that have not been certified by peer review.Analysis of genomics data is central to nearly all areas of modern biology. Despite significant progress in artificial intelligence (AI) and
L'Yi, Sehi +6 more
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Genomics and drug discovery [PDF]
, 2002 Genomics represents a new tool in drug discovery. Microbial genomics have been at the forefront of a new era of whole cell molecular biology because genomic data provides a quantum leap in available genetic data.
Hazell, Stuart L.
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Office of Public Health Genomics: State Public Health Genomics Programs: Implementing Evidence-Based Genomic Tests and Family Health History [PDF]
Since 2008, CDC, through the Office of Public Health Genomics (OPHG) and the Division of Cancer Prevention and Control (DCPC), has supported state genomics programs in Michigan, Oregon, and more recently Georgia, to implement evidence-based genomics ...
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Marine Population Genomics: Challenges and Opportunities
, 2019 Population genomics is revolutionizing biology and stimulating new research questions and directions. While human health has driven many of the genomics tools and approaches, all other biological fields have benefitted.
Marjorie F. Oleksiak +3 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source