Results 81 to 90 of about 844,050 (314)

Computational pan-genomics: Status, promises and challenges [PDF]

open access: yes, 2018
Many disciplines, from human genetics and oncology to plant breeding, microbiology and virology, commonly face the challenge of analyzing rapidly increasing numbers of genomes.
The Computational Pan-Genomics Consortium
core  

Genomic signatures and gene networking: challenges and promises

open access: yesBMC Genomics, 2011
This is an editorial report of the supplement to BMC Genomics that includes 15 papers selected from the BIOCOMP'10 - The 2010 International Conference on Bioinformatics & Computational Biology as well as other sources with a focus on genomics studies ...
Zhang Ke   +6 more
doaj   +1 more source

Anticipation of Personal Genomics Data Enhances Interest and Learning Environment in Genomics and Molecular Biology Undergraduate Courses. [PDF]

open access: yesPLoS ONE, 2015
An important discussion at colleges is centered on determining more effective models for teaching undergraduates. As personalized genomics has become more common, we hypothesized it could be a valuable tool to make science education more hands on ...
K Scott Weber   +2 more
doaj   +1 more source

Cancer Genomes [PDF]

open access: yesClinical Chemistry, 2010
10.1373/clinchem.2010.152140 ; Clinical Chemistry ; 56 ; 11 ; 1660-1664 ...
Diamandis, E.P.   +4 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Comparative BAC-based mapping in the white-throated sparrow, a novel behavioral genomics model, using interspecies overgo hybridization [PDF]

open access: yes, 2011
BACKGROUND The genomics era has produced an arsenal of resources from sequenced organisms allowing researchers to target species that do not have comparable mapping and sequence information.
Tuttle, Elaina M   +11 more
core   +1 more source

Genomics of Hypertension [PDF]

open access: yesPharmacological Research, 2017
A complex network of interacting pathways involving renal, neural, endocrine, vascular and other mechanisms controls the main determinants of blood pressure - cardiac output and total peripheral resistance. Multiple genes within each of these systems contribute to the specialized functions regulating blood pressure.
Padmanabhan, Sandosh   +2 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Common-pool resources and population genomics in Iceland, Estonia, and Tonga [PDF]

open access: yes, 2003
This paper addresses the application of the ethical concept of trust and the legal and political concept of public trust to population genomics projects in Iceland, Estonia, and Tonga.
Barker, Jeffrey H.
core  

Paths to a malaria vaccine illuminated by parasite genomics. [PDF]

open access: yes, 2015
More human death and disease is caused by malaria parasites than by all other eukaryotic pathogens combined. As early as the sequencing of the first human genome, malaria parasite genomics was prioritized to fuel the discovery of vaccine candidate ...
Conway, David J, Conway, David J.
core   +1 more source

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