Results 61 to 70 of about 821,457 (264)
Connecticut BRFSS genomics brief
1 online resource (4 pages) : color illustrationsAt head of title: Connecticut BRFSS genomics brief; "February 2014."; Includes bibliographical references (page ...
Foland, Joan, author
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Genomics and the intrinsic value of plants [PDF]
7 pages.Debates the ethical issues of plant genomics with respect to the intrinsic value of ...
Gremmen, Bart
core +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
PUBLIC HEALTH GENOMICS: THE ESSENTIALS
Tables and figures -- Foreword -- Preface -- The authors -- Introduction -- Pt. 1. Scientific and social perspectives on genomics -- Ch. 1. Past, present, and future of public health genomics -- Ch. 2. Genomics and the government -- Ch. 3.
Mikail, Claudia N.
core
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Routledge Handbook of Genomics, Health and Society
The Handbook provides an essential resource at the interface of Genomics, Health and Society, and forms a crucial research tool for both new students and established scholars across biomedicine and social sciences.
core
Generalized genetical genomics : advanced methods and applications [PDF]
Generalized genetical genomics (GGG) is a systems genetics approach that combines the analysis of genetic variation with population-wide assessment of variation in molecular traits in multiple environments to identify genotype-by-environment interactions.
Li, Yang,, Li, Yang
core +16 more sources
Functional genomics in Spiralia
Our understanding of the mechanisms that modulate gene expression in animals is strongly biased by studying a handful of model species that mainly belong to three groups: Insecta, Nematoda and Vertebrata.
Billie E Davies +9 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

