Results 61 to 70 of about 1,430,518 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Deep Learning of radiology-genomics integration for computational oncology: A mini review
Computational and Structural Biotechnology JournalIn the field of computational oncology, patient status is often assessed using radiology-genomics, which includes two key technologies and data, such as radiology and genomics.
Feng-ao Wang, Yixue Li, Tao Zeng
doaj +1 more source
Can an infectious disease genomics project predict and prevent the next pandemic? [PDF]
PLoS Biology, 2009 The world of genomics is transforming medicine, and is likely to influence the future development of new drugs, diagnostics, and vaccines. To date, the greater focus of genomics and medicine has been on conditions affecting resourcewealthy settings ...
Rajesh Gupta +2 more
doaj +1 more source
Ontology for genome comparison and genomic rearrangements
Comparative and Functional Genomics, 2004 AbstractWe present an ontology for describing genomes, genome comparisons, their evolution and biological function. This ontology will support the development of novel genome comparison algorithms and aid the community in discussing genomic evolution. It provides a framework for communication about comparative genomics, and a basis upon which further ...
Flanagan, K +4 more
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Frontiers in MedicineAimTo describe the implementation and evaluation of an education strategy called the globally networked learning-genomics (GNL-G) used in Master’s courses in Canada and Finland.
Jacqueline Limoges +3 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Blast2GO: A Comprehensive Suite for Functional Analysis in Plant Genomics
International Journal of Plant Genomics, 2007 Functional annotation of novel sequence data is a primary requirement for the utilization of functional genomics approaches in plant research. In this paper, we describe the Blast2GO suite as a comprehensive bioinformatics tool for functional annotation ...
A. Conesa, Stefan Götz
semanticscholar +1 more source
مجلة العلوم التربويةGenomics researchers have made a groundbreaking discovery regarding the relationship between a specific genome and various aspects of behavior, cognitive ability, skill acquisition, and educational attainment.
Hanaa Ouda Khadri
doaj +1 more source
Comparative and Functional Genomics, 2004 AbstractWith the development of genomic science and its battery of technologies, polar biology stands on the threshold of a revolution, one that will enable the investigation of important questions of unprecedented scope and with extraordinary depth and precision.
Clark, Melody S +11 more
openaire +2 more sources