Results 41 to 50 of about 844,050 (314)

Genomics Portals: integrative web-platform for mining genomics data

BMC Genomics, 2010
Background A large amount of experimental data generated by modern high-throughput technologies is available through various public repositories. Our knowledge about molecular interaction networks, functional biological pathways and transcriptional ...
Ghosh Krishnendu, Hu Zhen, Vineet Joshi K, Li Qian, Chen Jing, Johannes Freudenberg M, Phatak Mukta, Shinde Kaustubh, Meller Jaroslaw, Medvedovic Mario   +9 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

DesignGG: an R-package and web tool for the optimal design of genetical genomics experiments [PDF]

, 2009
BACKGROUND: High-dimensional biomolecular profiling of genetically different individuals in one or more environmental conditions is an increasingly popular strategy for exploring the functioning of complex biological systems.
Fu, Jingyuan; id_orcid, Swertz, Morris A.,, Jansen Ritsert C, Breitling, Rainer, Breitling, R., Jansen, R., Breitling, Rainer,, Li, Y., Vera, Gonzalo,, Swertz, Morris A., Breitling Rainer, Swertz Morris A, Vera Gonzalo, Swertz, M., Vera, G., Li, Yang,, Swertz, Morris A.; id_orcid, Fu, Jingyuan,, Fu, Jingyuan, Morris A Swertz, Jansen, Ritsert C.,, Jansen, Ritsert C., Vera, Gonzalo, Rainer Breitling, Gonzalo Vera, Ritsert C Jansen, Jingyuan Fu, Yang Li, Fu Jingyuan, Li Yang, Fu, J.Y., Vera Rodríguez, Gonzalo, Li, Yang   +32 more
core   +1 more source

A genomics learning framework for undergraduates.

PLoS ONE
Genomics is an increasingly important part of biology research. However, educating undergraduates in genomics is not yet a standard part of life sciences curricula.
Laura K Reed, Adam J Kleinschmit, Vincent Buonaccorsi, Arthur G Hunt, Douglas Chalker, Jason Williams, Christopher J Jones, Juan-Carlos Martinez-Cruzado, Anne Rosenwald   +8 more
doaj   +1 more source

Identifying factors that influence the use of pathogen genomics in Australia and New Zealand: a protocol

Frontiers in Public Health
IntroductionPathogen genomics, where whole genome sequencing technologies are used to produce complete genomic sequences of pathogens, is being increasingly used for infectious disease surveillance and outbreak response. Although proof-of-concept studies
James D. H. Ong, James D. H. Ong, Tehzeeb Zulfiqar, Kathryn Glass, Martyn D. Kirk, Brad Astbury, Angeline Ferdinand, Angeline Ferdinand, Angeline Ferdinand   +8 more
doaj   +1 more source

The future of genomics in Ireland – focus on genomics for health [version 1; peer review: 2 approved]

HRB Open Research, 2020
Genomics is revolutionizing biomedical research, medicine and healthcare globally in academic, public and industry sectors alike. Concrete examples around the world show that huge benefits for patients, society and economy can be accrued through ...
Cathal Seoighe, Adrian P. Bracken, Patrick Buckley, Peter Doran, Robert Green, Sandra Healy, David Kavanagh, Elaine Kenny, Mark Lawler, Maeve Lowery, Derek Morris, Darrin Morrissey, James J. O'Byrne, Denis Shields, Owen Smith, Charles A. Steward, Brian Sweeney, Walter Kolch   +17 more
doaj   +1 more source

Trends in : a statistical review of publications from 2003 to 2018 focusing on the most-studied genes and document clusters [PDF]

Genomics & Informatics, 2019
Genomics & Informatics (NLM title abbreviation: Genomics Inform) is the official journal of the Korea Genome Organization. Herein, we conduct a statistical analysis of the publications of Genomics & Informatics over the 16 years since its inception, with
Ji-Hyeon Kim, Hee-Jo Nam, Hyun-Seok Park
doaj   +1 more source

Combinations of genes at the 16p11.2 and 22q11.2 CNVs contribute to neurobehavioral traits.

PLoS Genetics, 2023
The 16p11.2 and 22q11.2 copy number variants (CNVs) are associated with neurobehavioral traits including autism spectrum disorder (ASD), schizophrenia, bipolar disorder, obesity, and intellectual disability.
Mikhail Vysotskiy, Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lauren A Weiss   +4 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

PUBLIC HEALTH GENOMICS: THE ESSENTIALS [PDF]

, 2008
Tables and figures -- Foreword -- Preface -- The authors -- Introduction -- Pt. 1. Scientific and social perspectives on genomics -- Ch. 1. Past, present, and future of public health genomics -- Ch. 2. Genomics and the government -- Ch. 3.
Mikail, Claudia N.
core