Results 31 to 40 of about 1,430,518 (311)

Using the Findings of a National Survey to Inform the Work of England’s Genomics Education Programme

Frontiers in Genetics, 2019
A national coordinated approach to workforce education and training in genomics is essential for the successful implementation of whole genome sequencing and, more broadly, genomic medicine within the National Health Service (NHS) in England.
Siobhan Simpson, Anneke Seller, Michelle Bishop   +2 more
doaj   +1 more source

Genome Projects and the Functional-Genomic Era [PDF]

Combinatorial Chemistry & High Throughput Screening, 2005
The problems we face today in public health as a result of the -- fortunately -- increasing age of people and the requirements of developing countries create an urgent need for new and innovative approaches in medicine and in agronomics. Genomic and functional genomic approaches have a great potential to at least partially solve these problems in the ...
Sauer, S., Konthur, Z., Lehrach, H.
openaire   +3 more sources

Phytozome: a comparative platform for green plant genomics

Nucleic Acids Res., 2011
The number of sequenced plant genomes and associated genomic resources is growing rapidly with the advent of both an increased focus on plant genomics from funding agencies, and the application of inexpensive next generation sequencing.
D. Goodstein, S. Shu, R. Howson, R. Neupane, Richard D. Hayes, Joni Fazo, T. Mitros, W. Dirks, U. Hellsten, Nicholas H. Putnam, D. Rokhsar   +10 more
semanticscholar   +1 more source

igv.js: an embeddable JavaScript implementation of the Integrative Genomics Viewer (IGV)

bioRxiv, 2020
igv.js is an embeddable JavaScript implementation of the Integrative Genomics Viewer (IGV). It can be easily dropped into any web page with a single line of code and has no external dependencies.
James T. Robinson, H. Thorvaldsdóttir, Douglass Turner, J. Mesirov   +3 more
semanticscholar   +1 more source

GENOME TREES AND THE NATURE OF GENOME EVOLUTION [PDF]

Annual Review of Microbiology, 2005
Genome trees are a means to capture the overwhelming amount of phylogenetic information that is present in genomes. Different formalisms have been introduced to reconstruct genome trees on the basis of various aspects of the genome. On the basis of these aspects, we separate genome trees into five classes: (a) alignment-free trees based on statistic ...
Snel, B., Huynen, M.A., Dutilh, B.E.
openaire   +3 more sources

The DisGeNET knowledge platform for disease genomics: 2019 update

Nucleic Acids Res., 2019
One of the most pressing challenges in genomic medicine is to understand the role played by genetic variation in health and disease. Thanks to the exploration of genomic variants at large scale, hundreds of thousands of disease-associated loci have been ...
J. González, J. Ramírez-Anguita, Josep Saüch-Pitarch, Francesco Ronzano, Emilio Centeno, F. Sanz, L. Furlong   +6 more
semanticscholar   +1 more source

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

Nucleic Acids Res., 2012
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database (www.cancerRxgene.org) is the largest public ...
Wanjuan Yang, Jorge Soares, Patricia Greninger, E. Edelman, H. Lightfoot, S. Forbes, Nidhi Bindal, D. Beare, James A. Smith, I. R. Thompson, Sridhar Ramaswamy, P. Futreal, D. Haber, M. Stratton, C. Benes, U. McDermott, M. Garnett   +16 more
semanticscholar   +1 more source

Genome Graphs and the Evolution of Genome Inference [PDF]

Genome Research, 2017
Abstract The human reference genome is part of the foundation of modern human biology, and a monumental scientific achievement. However, because it excludes a great deal of common human variation, it introduces a pervasive reference bias into the field of human genomics.
Paten, Benedict, Novak, Adam M., Eizenga, Jordan M., Erik, Garrison   +3 more
openaire   +4 more sources

miRBase: tools for microRNA genomics

Nucleic Acids Res., 2007
miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci from 58 species, expressing 5922 distinct mature miRNA sequences: a growth of
S. Griffiths-Jones, H. Saini, S. Dongen, Anton J. Enright   +3 more
semanticscholar   +1 more source

Preparing tomorrow's doctors for the genomics era: A nationwide survey of UK medical students

Future Healthcare Journal
Introduction: Low confidence in genomics knowledge among clinicians is a major barrier to the integration of genomics into mainstream medicine. Here, we assessed the genomics confidence of UK medical students approaching graduation. Methods: We conducted
Lydia Seed, Anna Scott, Michelle Peter, Shereen Tadros, Melissa Hill, Cristine Sortica da Costa   +5 more
doaj   +1 more source