Results 31 to 40 of about 1,315,416 (283)

Comparing large covariance matrices under weak conditions on the dependence structure and its application to gene clustering [PDF]

open access: yes, 2016
Comparing large covariance matrices has important applications in modern genomics, where scientists are often interested in understanding whether relationships (e.g., dependencies or co-regulations) among a large number of genes vary between different ...
Chang, Jinyuan   +3 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Genomics Portals: integrative web-platform for mining genomics data

open access: yesBMC Genomics, 2010
Background A large amount of experimental data generated by modern high-throughput technologies is available through various public repositories. Our knowledge about molecular interaction networks, functional biological pathways and transcriptional ...
Ghosh Krishnendu   +9 more
doaj   +1 more source

The future of genomics in Ireland – focus on genomics for health [version 1; peer review: 2 approved]

open access: yesHRB Open Research, 2020
Genomics is revolutionizing biomedical research, medicine and healthcare globally in academic, public and industry sectors alike. Concrete examples around the world show that huge benefits for patients, society and economy can be accrued through ...
Cathal Seoighe   +17 more
doaj   +1 more source

Trends in : a statistical review of publications from 2003 to 2018 focusing on the most-studied genes and document clusters [PDF]

open access: yesGenomics & Informatics, 2019
Genomics & Informatics (NLM title abbreviation: Genomics Inform) is the official journal of the Korea Genome Organization. Herein, we conduct a statistical analysis of the publications of Genomics & Informatics over the 16 years since its inception, with
Ji-Hyeon Kim, Hee-Jo Nam, Hyun-Seok Park
doaj   +1 more source

A genomics learning framework for undergraduates.

open access: yesPLoS ONE
Genomics is an increasingly important part of biology research. However, educating undergraduates in genomics is not yet a standard part of life sciences curricula.
Laura K Reed   +8 more
doaj   +1 more source

Identifying factors that influence the use of pathogen genomics in Australia and New Zealand: a protocol

open access: yesFrontiers in Public Health
IntroductionPathogen genomics, where whole genome sequencing technologies are used to produce complete genomic sequences of pathogens, is being increasingly used for infectious disease surveillance and outbreak response. Although proof-of-concept studies
James D. H. Ong   +8 more
doaj   +1 more source

Medicago truncatula functional genomics: an invaluable resource for studies on agriculture sustainability [PDF]

open access: yes, 2012
Legume functional genomics has moved many steps forward in the last two decades thanks to the improvement of genomics technologies and to the efforts of the research community.
Calderini, Ornella   +2 more
core  

The Chlamydomonas genome project: A decade on [PDF]

open access: yes, 2014
The green alga Chlamydomonas reinhardtii is a popular unicellular organism for studying photosynthesis, cilia biogenesis, and micronutrient homeostasis.
Aksoy, M   +19 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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