Results 11 to 20 of about 821,457 (264)

Genomic markers on synthetic genomes [PDF]

open access: yesEngineering in Life Sciences, 2021
AbstractGenome synthesis endows scientists the ability of de novo creating genomes absent in nature, by thorough redesigning DNA sequences and introducing numerous custom features. However, the genome synthesis is a labor‐ and time‐consuming work, and thus it is a challenge to verify and quantify the synthetic genome rapidly and precisely.
Hao‐Qian Zhao   +3 more
openaire   +3 more sources

Biobanks for genomics and genomics for biobanks [PDF]

open access: yesComparative and Functional Genomics, 2003
AbstractBiobanks include biological samples and attached databases. Human biobanks occur in research, technological development and medical activities. Population genomics is highly dependent on the availability of large biobanks. Ethical issues must be considered: protecting the rights of those people whose samples or data are in biobanks (information,
Cambon-Thomsen, Anne   +3 more
openaire   +5 more sources

Culex genome is not just another genome for comparative genomics [PDF]

open access: yesParasites & Vectors, 2012
أدى النشر الرسمي لتسلسل جينوم الباعوض إلى إغلاق مثلث ناقلات الأمراض البشرية من خلال مقابلة تسلسل جينوم Anopheles gambiae و Aedes aegypti. بالمقارنة مع هذه البعوضات الأخرى، تمتلك البعوضة الخماسية الفاشية العديد من الخصائص المميزة المحددة، وبالتالي قد توفر زوايا مختلفة للبحث مما يؤدي في النهاية إلى حل عملي للسيطرة على العبء المتزايد باستمرار للأمراض التي
Reddy, Niranjan Bp   +2 more
openaire   +7 more sources

Genomics and Functional Genomics of Alzheimer's Disease [PDF]

open access: yesNeurotherapeutics, 2022
Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disease. Due to its long clinical course and lack of an effective treatment, AD has become a major public health problem in the USA and worldwide. Due to variation in age-at-onset, AD is classified into early-onset (
openaire   +2 more sources

Genome Graphs and the Evolution of Genome Inference [PDF]

open access: yesGenome Research, 2017
Abstract The human reference genome is part of the foundation of modern human biology, and a monumental scientific achievement. However, because it excludes a great deal of common human variation, it introduces a pervasive reference bias into the field of human genomics.
Paten, Benedict   +3 more
openaire   +4 more sources

GENOME TREES AND THE NATURE OF GENOME EVOLUTION [PDF]

open access: yesAnnual Review of Microbiology, 2005
Genome trees are a means to capture the overwhelming amount of phylogenetic information that is present in genomes. Different formalisms have been introduced to reconstruct genome trees on the basis of various aspects of the genome. On the basis of these aspects, we separate genome trees into five classes: (a) alignment-free trees based on statistic ...
Snel, B., Huynen, M.A., Dutilh, B.E.
openaire   +3 more sources

Visualization for genomics: the Microbial Genome Viewer [PDF]

open access: yesBioinformatics, 2004
Abstract Summary: A Web-based visualization tool, the Microbial Genome Viewer, is presented that allows the user to combine complex genomic data in a highly interactive way. This Web tool enables the interactive generation of chromosome wheels and linear genome maps from genome annotation data stored in a MySQL database.
Robert Kerkhoven   +4 more
openaire   +5 more sources

u-Genome: A Database on Genome Design in Unicellular Genomes

open access: yesIn Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation, 2005
Unicellular eukaryotes were among the first ones to be selected for complete genome sequencing because of the small size of their genomes and their interactions with humans and a broad range of animals and plants. Currently, ten completely sequenced unicellular genome sequences have been publicly released and as the number of available unicellular ...
Sakharkar, K.R.   +5 more
openaire   +3 more sources

Cardiovascular Medicine and Genomics

open access: yes, 2020
Clinicians have always personalised patient management. There is a growing momentum to improve this further through the integration of genomic information into clinical care.
Watkins, H   +3 more
core   +1 more source

Genome Projects and the Functional-Genomic Era [PDF]

open access: yesCombinatorial Chemistry & High Throughput Screening, 2005
The problems we face today in public health as a result of the -- fortunately -- increasing age of people and the requirements of developing countries create an urgent need for new and innovative approaches in medicine and in agronomics. Genomic and functional genomic approaches have a great potential to at least partially solve these problems in the ...
Sauer, S., Konthur, Z., Lehrach, H.
openaire   +3 more sources

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