Results 71 to 80 of about 844,050 (314)

GENOMICS AND PUBLIC HEALTH: LEGAL AND SOCIO-ETHICAL PERSPECTIVES [PDF]

open access: yes, 2007
Acknowledgements -- Pt. I. Population screening: issues, realities and possibilities -- A Introduction: expansion of screening / J. Gerard Loeber -- Expansion of newborn screening: current achievements and new prospects / Bridget Wilcken ...
Knoppers, Bartha Maria, ed.
core  

Mathematics of the Genome

open access: yesFoundations of Computational Mathematics, 2016
This work gives a mathematical foundation for bifurcation from a stable equilibrium in the genome. We construct idealized dynamics associated with the genome. For this dynamics we investigate the two main bifurcations from a stable equilibrium. Finally, we give a mathematical framework for the Repressilator and the Toggle gene circuits.
Indika Rajapakse, Steve Smale
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Zebrafish: A Powerful Model for Genetics and Genomics [PDF]

open access: yes, 2023
Our understanding of fundamental biological mechanisms and the pathogenesis of human diseases has been greatly improved by studying the genetics and genomics of zebrafish [...
Cheol-Hee Kim, Seong-Kyu Choe
core   +1 more source

The Collaborative African Genomics Network (CAfGEN): Applying Genomic technologies to probe host factors important to the progression of HIV and HIV-tuberculosis infection in sub-Saharan Africa [version 1; peer review: 2 approved]

open access: yesAAS Open Research, 2018
Background: The Human Heredity and Health in Africa consortium (H3Africa) was conceived to facilitate the application of genomics technologies to improve health across Africa.
Gerald Mboowa   +24 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Genomics in the UK: mapping the social science landscape [PDF]

open access: yes, 2006
This paper has been prepared from the perspective of the ESRC Genomics Policy & Research Forum, which has the particular mandate of linking social science research on genomics with ongoing public and policy debates.
Suk, Jonathan E., Banner, Michael
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

GENOMICS IN ASIA: A CLASH OF BIOETHICAL INTERESTS? [PDF]

open access: yes, 2004
Contents -- Acknowledgements -- Introduction -- Ch. 1. Genomics in Asia: cultural values and bioethical practices / Margaret Sleeboom -- Pt. I. Religious perspectives -- Ch. 2. Ethical issues: an Islamic perspective / Anwar Nasim -- Ch. 3.
Sleeboom, Margaret, ed.
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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