Results 71 to 80 of about 927,032 (316)

Paths to a malaria vaccine illuminated by parasite genomics. [PDF]

open access: yes, 2015
More human death and disease is caused by malaria parasites than by all other eukaryotic pathogens combined. As early as the sequencing of the first human genome, malaria parasite genomics was prioritized to fuel the discovery of vaccine candidate ...
Conway, David J
core   +1 more source

yangxiaofeill/Papaver-Genomics: Papaver Genomics

open access: yes, 2021
This is the Genomics Data resource and analysis script of Papaver species genome. Currently, it includes Papaver somniferum (opium poppy), Papaver rhoeas (common poppy), and Papaver setigerum (troy poppy) genomic ...
yangxiaofeill
core   +1 more source

Cancer Genomes [PDF]

open access: yesClinical Chemistry, 2010
10.1373/clinchem.2010.152140 ; Clinical Chemistry ; 56 ; 11 ; 1660-1664 ...
Diamandis, E.P.   +4 more
openaire   +2 more sources

Precision Education Revolution: Identifying Future Requirements for Integrating Genomics into Educational Practices

open access: yesمجلة العلوم التربوية
Genomics researchers have made a groundbreaking discovery regarding the relationship between a specific genome and various aspects of behavior, cognitive ability, skill acquisition, and educational attainment.
Hanaa Ouda Khadri
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The Collaborative African Genomics Network (CAfGEN): Applying Genomic technologies to probe host factors important to the progression of HIV and HIV-tuberculosis infection in sub-Saharan Africa [version 1; peer review: 2 approved]

open access: yesAAS Open Research, 2018
Background: The Human Heredity and Health in Africa consortium (H3Africa) was conceived to facilitate the application of genomics technologies to improve health across Africa.
Gerald Mboowa   +24 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The Belgian DNA Debate: An Online Deliberative Platform on the Ethical, Legal, and Social Issues of Genomics

open access: yes, 2021
Introduction Genomics is increasingly being implemented in the society. To fully realise this implementation, citizens should be consulted about their perspectives on genomics and its associated ethical, legal, and social issues (ELSI) to enable them to ...
W. Van Hoof   +9 more
core   +1 more source

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