Results 121 to 130 of about 797,714 (339)
Scaling effects in the Penna ageing model [PDF]
arXiv, 2004 We have analysed the possibility of scaling the sexual Penna ageing model. Assuming that the number of genes expressed before the reproduction age grows linearly with the genome size and that the mutation rate per genome and generation is constant, we have found that the fraction of defective genes expressed before the minimum reproduction age drops ...
arxiv
The Genomic Complexity of Acanthamoeba castellanii Mitochondrial DNA [PDF]
, 1974 Hans J. Bohnert, Reinhold G. Herrmann
openalex +1 more source
Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
wiley +1 more source
Ultraconserved Sequences in the Honeybee Genome - Are GC-rich Regions Preferred? [PDF]
Systemix Reports 2, Feb. 18 (2007), 2007 Among all insect genomes, honeybee displays one of the most unusual patterns with interspersed long AT and GC-rich segments. Nearly 75% of the protein-coding genes are located in the AT-rich segments of the genome, but the biological significance of the GC-rich regions is not well understood.
arxiv
Methylation pattern of genomic RNA from Moloney murine leukemia virus [PDF]
, 1976 Maurice C. Bondurant +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Deep Learning of radiology-genomics integration for computational oncology: A mini review
Computational and Structural Biotechnology JournalIn the field of computational oncology, patient status is often assessed using radiology-genomics, which includes two key technologies and data, such as radiology and genomics.
Feng-ao Wang, Yixue Li, Tao Zeng
doaj
A Compressed Self-Index for Genomic Databases [PDF]
arXiv, 2011 Advances in DNA sequencing technology will soon result in databases of thousands of genomes. Within a species, individuals' genomes are almost exact copies of each other; e.g., any two human genomes are 99.9% the same. Relative Lempel-Ziv (RLZ) compression takes advantage of this property: it stores the first genome uncompressed or as an FM-index, then
arxiv
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source