Results 141 to 150 of about 1,946,862 (417)
, 2012 This paper describes the development of an audio visual genomics glossary that was designed as an education tool for American Indian communities. This “Talking Glossary of Genomics Terminology” is a multimedia DVD that was modeled on the “Talking ...
Coe, Kathryn +3 more
core
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
GMOL: An Interactive Tool for 3D Genome Structure Visualization [PDF]
arXiv, 2015 It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there still exists a shortage of tools dedicated to visualizing the genome.
arxiv
VISTA: computational tools for comparative genomics
Nucleic Acids Res., 2004 Comparison of DNA sequences from different species is a fundamental method for identifying functional elements in genomes. Here, we describe the VISTA family of tools created to assist biologists in carrying out this task. Our first VISTA server at http:/
K. Frazer +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Rubbish DNA: The functionless fraction of the human genome [PDF]
arXiv, 2016 Because genomes are products of natural processes rather than intelligent design, all genomes contain functional and nonfunctional parts. The fraction of the genome that has no biological function is called rubbish DNA. Rubbish DNA consists of junk DNA, i.e., the fraction of the genome on which selection does not operate, and garbage DNA, i.e ...
arxiv
Phandango: an interactive viewer for bacterial population genomics
bioRxiv, 2017 Summary Fully exploiting the wealth of data in current bacterial population genomics datasets requires synthesising and integrating different types of analysis across millions of base pairs in hundreds or thousands of isolates.
J. Hadfield +5 more
semanticscholar +1 more source
Frontiers in Plant Science, 2013 BRASSICA GENOME RESEARCH TOPIC Brassica species include important crops and provide unique materials for the study of genome evolution. These crops include six important vegetables and oilseed crops, which have been classically described by “U’s triangle’. The three diploid species B. rapa (A genome), B. nigra (B genome), and B.
Michael Freeling, Xiaowu Wang
openaire +4 more sources
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
Metagenomics: Application of Genomics to Uncultured Microorganisms
Microbiology and Molecular Biology Reviews, 2004 SUMMARY Metagenomics (also referred to as environmental and community genomics) is the genomic analysis of microorganisms by direct extraction and cloning of DNA from an assemblage of microorganisms.
J. Handelsman
semanticscholar +1 more source