Results 141 to 150 of about 1,430,606 (347)

Deep Learning of radiology-genomics integration for computational oncology: A mini review

Computational and Structural Biotechnology Journal
In the field of computational oncology, patient status is often assessed using radiology-genomics, which includes two key technologies and data, such as radiology and genomics.
Feng-ao Wang, Yixue Li, Tao Zeng
doaj  

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Selective Packaging of Host tRNA's by Murine Leukemia Virus Particles Does Not Require Genomic RNA [PDF]

, 1979
Judith G. Levin, J.G. Seidman
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

The Ectocarpus Genome and Brown Algal Genomics

, 2012
Brown algae are important organisms both because of their key ecological roles in coastal ecosystems and because of the remarkable biological features that they have acquired during their unusual evolutionary history. The recent sequencing of the complete genome of the filamentous brown alga Ectocarpus has provided unprecedented access to the molecular
Colin Brownlee, Betsy A. Read, Hiroshi Kawai, Stefan A. Rensing, Sylvie Doulbeau, Patrick Wincker, Bank Beszteri, Bank Beszteri, Florian Maumus, Chris Bowler, Martina Strittmatter, John H. Bothwell, John H. Bothwell, John H. Bothwell, Taizo Motomura, Véronique Anthouard, Pascal J. Lopez, Thierry Tonon, Thierry Tonon, Martin Lohr, Erwan Corre, Carolyn A. Napoli, Catherine Leblanc, Catherine Leblanc, Olivier Godfroy, Olivier Godfroy, Takahiro Yamagishi, Claire Jubin, Corinne Da Silva, Alok Arun, Alok Arun, Hadi Quesneville, Simon M. Dittami, Simon M. Dittami, Julie Poulain, Akira F. Peters, Akira F. Peters, Eric Bonnet, Eric Bonnet, Julia Morales, Julia Morales, Grigoris D. Amoutzias, Grigoris D. Amoutzias, Hervé Moreau, Philippe Potin, Philippe Potin, Remy Luthringer, Remy Luthringer, James W. Tregear, Cindy Martens, Daniel Lang, Claire M. M. Gachon, Gurvan Michel, Gurvan Michel, J. Mark Cock, J. Mark Cock, Garry Farnham, Jonathan H. Badger, Svenja Heesch, Svenja Heesch, Sophia Ahmed, Sophia Ahmed, Pierre Rouzé, Ga Youn Cho, Ga Youn Cho, Marek Eliáš, Laurence Dartevelle, Laurence Dartevelle, Peter von Dassow, Patrice Lerouge, Nicolas Macaisne, Nicolas Macaisne, Yves Van de Peer, David R. Nelson, Carl J. Carrano, Ludovic Delage, Ludovic Delage, Frithjof C. Küpper, Frithjof C. Küpper, François Artiguenave, Delphine Scornet, Delphine Scornet, Andrés Ritter, Andrés Ritter, Andrés Ritter, Manoj P. Samanta, Bénédicte Charrier, Bénédicte Charrier, Kamel Jabbari, Chikako Nagasato, Jean-Marc Aury, Klaus Valentin, Bernard Kloareg, Bernard Kloareg, Pi Nyvall-Collén, Pi Nyvall-Collén, Gaelle Samson, Catherine Boyen, Catherine Boyen, Gildas Le Corguillé, Bernhard Gschloessl, Bernhard Gschloessl, Diego Miranda-Saavedra, Kenny Billiau, Nicolas Delaroque, Jonas Collén, Jonas Collén, Andrew E. Allen, Susana M. Coelho, Susana M. Coelho, Declan C. Schroeder, Béatrice Segurens, Aude Le Bail, Aude Le Bail, Kei Kimura, Lieven Sterck, Sylvie Rousvoal, Sylvie Rousvoal, Cyril Pommier   +118 more
openaire   +4 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

A 26-base-pair repetitive sequence specific for Neisseria gonorrhoeae and Neisseria meningitidis genomic DNA [PDF]

, 1986
F F Correia, S Inouye, Masayori Inouye
openalex   +1 more source

A long road ahead to reliable and complete medicinal plant genomes

Nature Communications
Long-read DNA sequencing has propelled medicinal plant genomics forward, with over 400 genomes from 203 plants sequenced by February 2025. However, many genomes still have assembly and annotation flaws, with only 11 gapless telomere-to-telomere ...
Ling-Tong Cheng, Zi-Long Wang, Qian-Hao Zhu, Min Ye, Chu-Yu Ye   +4 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source