Results 111 to 120 of about 1,113,934 (309)
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
THE ACADEMICIAN N.I. VAVILOV AND INTRODUCTION OF RICE IN RUSSIA
Зерновое хозяйство России, 2018 The article considers the role of N.I. Vavilov in creating the theory of introduction of plants. N.I. Vavilov was the first who showed the possibility and practicability of expanding rice from the southern parts of the country to the northern ones ...
A. V. Chamyshev
doaj
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Genotype-Year interaction ANOVA for fresh yield studied during three years.
Genotype-Year interaction ANOVA for fresh yield studied during three years.
Md. Ashraful Alam (7434188) +12 more
core +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Immunity, Inflammation and DiseaseBackground As the social economy has developed and population mobility has increased, differences in the Human immunodeficiency virus type 1 (HIV‐1) genotype distribution among men who have sex with men (MSM) have become apparent in the provinces and ...
Dawen Qin +7 more
doaj +1 more source
Thalassemia: genotypes and phenotypes
Annals of Hematology, 1991 The large degree of phenotypic heterogeneity of thalassemia can now be related to the underlying genomic defects. This information has accumulated rapidly over the last years through the recent advances in molecular technology. The list of main types of thalassemia (alpha or beta) that can be differentiated includes several gene deletions (complete or ...
openaire +5 more sources
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Journal of Natural FibersThe study, comprised seventeen genotypes, was conducted during 2016 to 2019 growing seasons. The design was Randomized Complete Block Design (RCBD) with three replications to identify adaptable cotton genotypes.
Fiseha Baraki +8 more
doaj +1 more source