Results 171 to 180 of about 2,216,855 (328)

Global epidemiology and genotype distribution of the hepatitis C virus infection.

Journal of Hepatology, 2014
E. Gower, C. Estes, S. Blach, K. Razavi-Shearer, H. Razavi   +4 more
semanticscholar   +1 more source

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

Advanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni, Chengcheng Yang, Junqi Zhang, Zhou Hang, Ming Zheng, Dengyuan Feng, Qinghuan Shen, Jinxu Miao, Xulin Sun, Li Sun, Baixin Shen, Min Gu, Zijie Wang   +12 more
wiley   +1 more source

Influence of Genotype and Mineral Nutrition on the Distribution of Growth within Plants of Lolium perenne L. grown in Soil [PDF]

, 1968
Arthur Troughton
openalex   +1 more source

Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection.

New England Journal of Medicine, 2015
J. Feld, I. Jacobson, C. Hézode, T. Asselah, P. Ruane, N. Gruener, A. Abergel, A. Mangia, Ching‐lung Lai, H. L. Chan, F. Mazzotta, Christophe Moreno, E. Yoshida, S. Shafran, W. Towner, T. Tran, J. McNally, A. Osinusi, E. Svarovskaia, Yanni Zhu, D. Brainard, J. Mchutchison, K. Agarwal, S. Zeuzem   +23 more
semanticscholar   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

The impact of the BDNF Val66Met genotype on intrusive memories following trauma exposure and in PTSD is moderated by sex and timing of trauma exposure. [PDF]

Sci Rep
Nicholson EL, Garry M, Ney LJ, Hsu KCM, Zuj DV, Felmingham KL.   +5 more
europepmc   +1 more source

Photoperiod, Temperature and Genotype Interactions Affecting Time of Flowering in Beans, Phaseolus vulgaris L.1 [PDF]

, 1969
D. S. Padda, H. M. Munger
openalex   +1 more source

Predictive genotype [PDF]

Canadian Medical Association Journal, 2010
Shinya, Ito, Bruce C, Carleton
openaire   +2 more sources

Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2018
C. Gardner, J. Trepanowski, Liana C. Del Gobbo, Michelle E. Hauser, J. Rigdon, J. Ioannidis, M. Desai, A. King   +7 more
semanticscholar   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source