Results 41 to 50 of about 9,640,965 (252)
The objectives of this study were a description of the Centroid Method, which is used to investigate the phenotypic adaptability of genotypes and the inclusion of new ideotypes therein, creating the Integrated Method for adaptability and phenotypic ...
Edmar Soares de Vasconcelos +4 more
doaj +1 more source
Soybean is a crop in high demand, in particular as a crucial source of plant protein. As a short-day plant, soybean is sensitive to the latitude of the growing site. Consequently, varieties that are well adapted to higher latitudes are required to expand
Cleo A. Döttinger +3 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Genotype-Environment Interaction in Wheat
Thirteen advance lines and three check varieties viz. , Chakwal-86, Pak-81 and Rawal-87 of wheat were planted at nine locations to estimate genotype x environment interaction.
Ashraf, Muhammad +3 more
core +1 more source
Review on Genotype X Environment Interaction in Plant Breeding and Agronomic Stability of Crops [PDF]
G×E is defined as a phenomenon that phenotypes respond to genotypes differently according to different environmental factors. The concept of genotype-environment interactions leads to measure the agronomic stability of the genotype and under the ...
Zakir, Mohammedsani
core +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Genotype-environment interaction in evaluating yielding of selected edible potato*(Solanum tuberosum L.) cultivars [PDF]
In the research carried out in the years 1999-2001 the following characteristics of three edible potato cultivars were determined: tuber yield, starch content, dry matter content, vitamin C content and starch yield.
Bombik, Antoni, Rymuza, Katarzyna
core +2 more sources
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

