Advanced Healthcare Materials, EarlyView.A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu +19 more
wiley +1 more source
Subclinical hepatitis E virus genotype 1 infection: The concept of "dynamic human reservoir". [PDF]
World J HepatolShrestha A, Basnet S, Kc S.
europepmc +1 more source
Characterization of a Novel Hepatitis C Virus Genotype 1 Subtype from a Patient Failing 4 Weeks of Glecaprevir-Pibrentasvir Treatment. [PDF]
Microbiol Resour Announc, 2021 Pedersen MS +5 more
europepmc +1 more source
Advanced Materials, EarlyView.We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena +7 more
wiley +1 more source
Analysis of Piscine orthoreovirus genotype 1 genomes collected over a 32-year period (1988-2020) suggests a fitness peak in salmon hosts with minimal evidence for temporal divergence. [PDF]
Virus EvolJohnson SC +4 more
europepmc +1 more source
The Relationship Between HCV-NS5A Gene Mutations and Resistance to Combination Therapy in Patients with HCV- Genotype 1-B. [PDF]
Rep Biochem Mol Biol, 2021 Lashgarian HE +4 more
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Collision‐Resilient Winged Drones Enabled by Tensegrity Structures
Advanced Robotics Research, EarlyView.Based on structures of birds such as the woodpeck, this article presents the collision‐resilient aerial robot, SWIFT. SWIFT leverages tensegrity structures in the fuselage and wings which allow it to undergo large deformations in a crash, without sustaining damage. Experiments show that SWIFT can reduce impact forces by 70% over conventional structures.
Omar Aloui +5 more
wiley +1 more source
Isolation, Identification, and Pathogenicity of a Goose Astrovirus Genotype 1 Strain in Goslings in China. [PDF]
VirusesWei F, He D, Wu B, Diao Y, Tang Y.
europepmc +1 more source
Evaluation of hepatitis E antigen kinetics and its diagnostic utility for prediction of the outcomes of hepatitis E virus genotype 1 infection. [PDF]
Virulence, 2021 El-Mokhtar MA +11 more
europepmc +1 more source
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source