Results 251 to 260 of about 1,259,951 (349)

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Chronic hepatitis C genotype 6 responds better to pegylated interferon and ribavirin combination therapy than genotype 1 [PDF]

, 2009
Owen T‐Y Tsang, J. Zee, Jacky M‐C Chan, Reggie S‐T Li, Yee‐Man Kan, F.T.W. Li, F H Lo, DAVID ALAN CHOW, Kent W‐L Cheung, Kam‐Hon Chan, Yat‐Wah Yeung, Fook–Hong Ng, Michael K. K. Li, W K Kwan, Thomas S‐T Lai   +14 more
openalex   +1 more source

Effectiveness of Ledipasvir-Sofosbuvir 12 Weeks After Hepatitis C Virus Genotype 1 Infection and the Factors Associated With Sustained Virologic Response: A Retrospective Study. [PDF]

Cureus
Alshoaibi IA, Al-Gamli A, Abdullah M, Abdo B, Alzanen KH, Alhakamy M, Al-Namer M, Ahmed F, Tamesh M, Mahdi W, Abdo Z, Mohammed M.   +11 more
europepmc   +1 more source

Differences between predicted outer membrane proteins of genotype 1 and 2 Mannheimia haemolytica. [PDF]

BMC Microbiol, 2020
Clawson ML, Schuller G, Dickey AM, Bono JL, Murray RW, Sweeney MT, Apley MD, DeDonder KD, Capik SF, Larson RL, Lubbers BV, White BJ, Blom J, Chitko-McKown CG, Brichta-Harhay DM, Smith TPL.   +15 more
europepmc   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Determination of the High Prevalence of Dual/Mixed- or X4-Tropism Among HIV Type 1 CRF01_AE in Hong Kong by Genotyping and Phenotyping Methods

, 2013
Sabrina Wai-Chi To, Jonathan Hon-Kwan Chen, Ka-Hing Wong, Kenny Chi-Wai Chan, Zhiwei Chen, Wing-Cheong Yam   +5 more
openalex   +2 more sources

Colon-derived Caco-2 cells support replication of hepatitis E virus genotype 1 strain Sar55 generated by reverse genetics. [PDF]

Virus Res
Falkenhagen A, Panajotov J, Johne R.
europepmc   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Sofosbuvir based regimens in the treatment of chronic hepatitis C genotype 1 infection in African–American patients: a community-based retrospective cohort study

, 2018
Vijay Gayam, Benjamin Tiongson, Mazin Khalid, Amrendra Mandal, Osama Mukhtar, Arshpal Gill, Pavani Garlapati, Binav Shrestha, Mowyad Khalid, Sandipan Chakraborty, Debra Guss, Jagannath Sherigar, Mohammed A. Mansour, Smruti R. Mohanty   +13 more
openalex   +1 more source

Cow's milk consumption, HLA-DQB1 genotype, and type 1 diabetes: a nested case-control study of siblings of children with diabetes. Childhood diabetes in Finland study group. [PDF]

, 2000
Suvi Μ. Virtanen, E. Läärä, Elina Hyppönen, Helena Reijonen, Leena Räsänen, A. Aro, Mikael Knip, Jorma Ilonen, Hans K. Åkerblom   +8 more
openalex   +1 more source