Results 21 to 30 of about 26,046,977 (327)

Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.

New England Journal of Medicine, 2014
BACKGROUND Effective treatment for hepatitis C virus (HCV) genotype 1 infection in patients who have not had a sustained virologic response to prior interferon-based therapy represents an unmet medical need.
N. Afdhal, K. Reddy, D. Nelson, E. Lawitz, S. Gordon, E. Schiff, R. Nahass, R. Ghalib, N. Gitlin, R. Herring, J. Lalezari, Z. Younes, P. Pockros, A. D. Di Bisceglie, Sanjeev Arora, G. Subramanian, Yanni Zhu, H. Dvory‐Sobol, Jenny C. Yang, P. Pang, W. Symonds, J. Mchutchison, A. Muir, M. Sulkowski, P. Kwo   +24 more
semanticscholar   +1 more source

Cost-effectiveness of antiviral therapy in treatment-naive patients with chronic hepatitis C (genotype 1)

Журнал инфектологии, 2017
Interferon-free therapy for genotype 1 hepatitis C are preferable from the point of view of clinical effectiveness and safety.The purpose of work was the assessment of costs and costeffectiveness of regimens for the treatment of HCV (1 genotype) at the ...
A. V. Rudakova, D. A. Gusev, A. N. Uskov, L. N. Konovalova, Yu. V. Lobzin   +4 more
doaj   +1 more source

Rabies: an evidence-based approach to management

South African Family Practice, 2007
Human rabies in South Africa is largely due to infection with the classical rabies virus (genotype 1), with the yellow mongoose the commonest vector except in KwaZulu-Natal, Eastern Cape, Mpumalanga and now Limpopo provinces where the dog is ...
L. Blumberg, J. Weyer, J. Frean, G.A. Ogunbanjo   +3 more
doaj   +1 more source

Genetic diversity of hepatitis D virus genotype‐1 in Europe allows classification into subtypes

Journal of Viral Hepatitis, 2019
Hepatitis delta virus (HDV) is an RNA virus which leads to both acute and chronic forms of hepatitis. At present, HDV isolates have been classified into eight major genotypes distributed over different geographical regions.
H. Karimzadeh, Z. Usman, D. Frishman, M. Roggendorf   +3 more
semanticscholar   +1 more source

Neurofibromatosis type 1: from genotype to phenotype [PDF]

Journal of Medical Genetics, 2012
Although neurofibromatosis 1 (NF1) is a common Mendelian disorder with autosomal-dominant inheritance, its expression is highly variable and unpredictable. Many NF1 patients have been genotyped but few allele-phenotype correlations have been identified.
Eric, Pasmant, Michel, Vidaud, Dominique, Vidaud, Pierre, Wolkenstein   +3 more
openaire   +2 more sources

Performance of assays for testing antibodies against porcine reproductive and respiratory syndrome virus in sera collected from swine farms in a region with an extreme virus heterogeneity [PDF]

, 2014
Porcine reproductive and respiratory syndrome is the most economically important viral disease in the swine industry worldwide. Porcine reproductive and respiratory syndrome virus (PRRSV) strains are classified into two distinct genotypes, the European ...
Karniychuk, U Uladzimir, Nauwynck, Hans
core   +2 more sources

Isolation and complete genome sequencing of rabies virus strain isolated from a brown bear (Ursus arctos) that attacked a human in Primorsky krai (November, 2014)

Вопросы вирусологии, 2016
An attack of a brown bear (Ursus arctos) on human was detected in November, 2014 in the Barabash village (Khasan region of the Primorski krai) located in close proximity to the national park Land of the Leopard. The bear was shot. The deviant behavior of
M. Yu. Shchelkanov, A. A. Deviatkin, V. Yu. Ananiev, E. V. Frolov, I. E. Dombrovskaya, V. G. Dedkov, A. V. Ardashev, S. A. Kolomeets, I. P. Korotkova, E. N. Lyubchenko, V. V. Bandeev, M. N. Prosyannikova, I. V. Galkina, E. S. Ivanushko, N. P. Emelyanova, N. I. Baranov, S. A. Ulyanova, S. V. Aramilev, P. V. Fomenko, A. L. Surovy, N. A. Poroshin, N. N. Sokol, D. V. Maslov, E. E. Makhinya, G. A. Shipulin   +24 more
doaj   +1 more source

Effect of the Strawberry Genotype, Cultivation and Processing on the Fra a 1 Allergen Content [PDF]

, 2018
Birch pollen allergic patients show cross-reactivity to vegetables and fruits, including strawberries (Fragaria × ananassa). The objective of this study was to quantify the level of the Fra a 1 protein, a Bet v 1-homologous protein in strawberry fruits
Kock, V., Kurze, E., Lo Scalzo, R, Olbricht, K., Schwab, Wilfried   +4 more
core   +2 more sources

Glecaprevir and pibrentasvir for 12 weeks for hepatitis C virus genotype 1 infection and prior direct‐acting antiviral treatment

Hepatology, 2017
Although direct‐acting antiviral (DAA) therapies for chronic hepatitis C virus (HCV) infection have demonstrated high rates of sustained virologic response, virologic failure may still occur, potentially leading to the emergence of viral resistance ...
F. Poordad, F. Felizarta, A. Asatryan, M. Sulkowski, R. Reindollar, C. Landis, S. Gordon, S. Flamm, M. Fried, D. Bernstein, Chih‐Wei Lin, Ran Liu, Sandra S. Lovell, T. Ng, J. Kort, F. Mensa   +15 more
semanticscholar   +1 more source

Including copy number variation in association studies to predict genotypic values [PDF]

, 2010
The objective of this study was to investigate, both empirically and deterministically, the ability to explain genetic variation resulting from a copy number polymorphism (CNP) by including the CNP, either by its genotype or by a continuous derivation ...
Calus, M.P.L., Haley, C.S., Koning, de, D.J.   +2 more
core   +2 more sources