Results 11 to 20 of about 1,259,951 (349)
Interferon and ribavirin therapy for chronic hepatitis C virus genotype 6: A comparison with genotype 1 [PDF]
Because there is a lack of data on the treatment outcome of patients who carry hepatitis C virus (HCV) genotype 6, we conducted a prospective study, to compare the effect of interferon and ribavirin therapy in HCV genotypes 1 and 6, of patients with ...
Chan, AOO +5 more
core +6 more sources
Hepatitis E Virus Genotype 1, Cuba
nunca llevados a los sitios donde fueron alojados o sacados para pastoreo. Por lo tanto, la única forma de infectar al bebé sería la exposición ambiental. Dado que el bebé no había sido llevado a los sitios de los animales, el patógeno debe haber sido transmitido a la casa por la ropa o la piel del padre o abuelo, que había estado pastoreando a los ...
María de la Caridad Montalvo Villalba +6 more
doaj +3 more sources
Interleukin-1 Genotype in Periodontitis [PDF]
This paper presents the current knowledge concerning the role of polymorphisms of IL1A and IL1B genes in periodontitis. Attention has been paid to the role of IL-1 in the pathogenesis of the disease, and to the significance of a genetic test, investigating the presence of composite two polymorphisms of IL-1 gene, as a risk factor for severe ...
Aniela Brodzikowska +2 more
openaire +2 more sources
Neuregulin 1 Genotype and Schizophrenia [PDF]
The neuregulin 1 (NRG1) gene has been the subject of considerable excitement within the psychiatric genetics literature since it was originally identified as a potential susceptibility locus for schizophrenia. Here we provide an update of our first meta-analysis of this association.
Munafò, MR, Attwood, A, Flint, J
openaire +2 more sources
Optimal therapy in genotype 1 patients [PDF]
AbstractMost infections with hepatitis C virus (HCV) fail to resolve spontaneously and progress to chronic hepatitis C. Genotype 1 HCV accounts for most hepatitis C infections in North America, Western Europe, and Japan. Patients infected with HCV genotype 1 are the most resistant to treatment, which results in poor treatment outcomes.
Harald, Farnik +2 more
openaire +2 more sources
Evaluation of the GTI-ASP-1 platelet antigen genotyping kit for the determination of the HPA-1 genotype [PDF]
The human platelet antigen system HPA-1 is involved in most cases of neonatal alloimmune thrombocytopenia and posttransfusion purpura, and occasionally causes refractoriness to platelet transfusions. Complete concordance was obtained in genotyping for HPA-1 in all samples tested with the HPA-1 genotyping kit and a ligation-based typing method. However,
Legler, T. J., Hagner, C., Köhler, M.
openaire +3 more sources
Faldaprevir and Deleobuvir for HCV Genotype 1 Infection [PDF]
BACKGROUND: Interferon-free regimens would be a major advance in the treatment of patients with chronic hepatitis C virus (HCV) infection. METHODS: In this phase 2b, randomized, open-label trial of faldaprevir (a protease inhibitor) and deleobuvir (a nonnucleoside polymerase inhibitor), we randomly assigned 362 previously untreated patients with HCV ...
Zeuzem, Stefan +16 more
openaire +3 more sources
Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]
Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Alicia R. Feagins +15 more
core +1 more source
Introduction: The WHO estimates that 180 million people are chronically infected with hepatitis C virus (HCV) throughout the world. Despite the emergence of new therapies, the combination of pegylated interferon and ribavirin remains the accepted ...
Jorge Luis Sandoval-Ramirez +3 more
doaj +1 more source
(1) Background: Periodontitis is a chronic multifactorial inflammatory disease associated with dysbiotic plaque biofilms and characterized by progressive destruction of the tooth-supporting apparatus.
Aniela Brodzikowska +2 more
doaj +1 more source

