Results 11 to 20 of about 735,853 (255)
Viruses, 2021 Hepatitis E virus (HEV) can account for up to a 30% mortality rate in pregnant women, with highest incidences reported for genotype 1 (gt1) HEV. Reasons contributing to adverse maternal-fetal outcome during pregnancy in HEV-infected pregnant women remain
Kush K. Yadav +3 more
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Optimal therapy in genotype 1 patients [PDF]
Liver International, 2009 AbstractMost infections with hepatitis C virus (HCV) fail to resolve spontaneously and progress to chronic hepatitis C. Genotype 1 HCV accounts for most hepatitis C infections in North America, Western Europe, and Japan. Patients infected with HCV genotype 1 are the most resistant to treatment, which results in poor treatment outcomes.
Harald, Farnik +2 more
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Evaluation of the GTI-ASP-1 platelet antigen genotyping kit for the determination of the HPA-1 genotype [PDF]
Immunohematology, 1998 The human platelet antigen system HPA-1 is involved in most cases of neonatal alloimmune thrombocytopenia and posttransfusion purpura, and occasionally causes refractoriness to platelet transfusions. Complete concordance was obtained in genotyping for HPA-1 in all samples tested with the HPA-1 genotyping kit and a ligation-based typing method. However,
Legler, T. J., Hagner, C., Köhler, M.
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Faldaprevir and Deleobuvir for HCV Genotype 1 Infection [PDF]
New England Journal of Medicine, 2013 BACKGROUND: Interferon-free regimens would be a major advance in the treatment of patients with chronic hepatitis C virus (HCV) infection. METHODS: In this phase 2b, randomized, open-label trial of faldaprevir (a protease inhibitor) and deleobuvir (a nonnucleoside polymerase inhibitor), we randomly assigned 362 previously untreated patients with HCV ...
Zeuzem, Stefan +16 more
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Вопросы вирусологии, 2017 The main reason for the ineffectiveness of antiviral therapy in patients with chronic hepatitis C that impedes full and adequate treatment of IFN-α and ribavirin is the development of neutropenia and thrombocytopenia.
E. R. Manapova +2 more
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Journal of Infection in Developing Countries, 2015 Introduction: The WHO estimates that 180 million people are chronically infected with hepatitis C virus (HCV) throughout the world. Despite the emergence of new therapies, the combination of pegylated interferon and ribavirin remains the accepted ...
Jorge Luis Sandoval-Ramirez +3 more
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Biomedicines, 2023 (1) Background: Periodontitis is a chronic multifactorial inflammatory disease associated with dysbiotic plaque biofilms and characterized by progressive destruction of the tooth-supporting apparatus.
Aniela Brodzikowska +2 more
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Cost-effectiveness of antiviral therapy in chronic hepatitis C (G1)
Журнал инфектологии, 2016 Updated HCV clinical guidelines placed direct acting agents (DAAs) as the preferable the first line regimens.The objective of the study was PE assessment of HCV therapy among G1 naïve patientsMethods: Analysis is based on data of randomized clinical ...
A. V. Rudakova +3 more
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Журнал инфектологии, 2017 Interferon-free therapy for genotype 1 hepatitis C are preferable from the point of view of clinical effectiveness and safety.The purpose of work was the assessment of costs and costeffectiveness of regimens for the treatment of HCV (1 genotype) at the ...
A. V. Rudakova +4 more
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Neurofibromatosis type 1: from genotype to phenotype [PDF]
Journal of Medical Genetics, 2012 Although neurofibromatosis 1 (NF1) is a common Mendelian disorder with autosomal-dominant inheritance, its expression is highly variable and unpredictable. Many NF1 patients have been genotyped but few allele-phenotype correlations have been identified.
Eric, Pasmant +3 more
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