Results 291 to 300 of about 26,046,977 (327)

Hepatitis C virus genotype 4: Genotype 1's little brother

Journal of Viral Hepatitis, 2016
SummaryTreatment for hepatitis C virus genotype 4 infection has undergone a major advance over the past 5 years with the emergence of direct‐acting antiviral agents. Previously, genotype 4 treatment had been limited to the combination of pegylated interferon and ribavirin, with low rates of sustained virological response. The combinations of new direct‐
J, Llaneras, M, Riveiro-Barciela, M, Buti, R, Esteban   +3 more
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Natural history of chronic hepatitis C: Genotype 1 versus genotype 6

Journal of Hepatology, 2010
Data on the natural history of chronic hepatitis C virus (HCV) genotype 6 is lacking.We compared the natural history of 138 HCV genotype 1 patients (median age: 50) with 78 HCV genotype 6 patients (median age: 46.5). Baseline demographic data including gender, route of transmission, liver biochemistry, HCV RNA levels, and serial alanine ...
Yuen, MF, Wong, DKH, Hung, I, Fung, J, Lai, CL, Seto, WK, Yuen, J, Young, J   +7 more
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Treatment of Chronic HCV Genotype 1 Coinfection

Current HIV/AIDS Reports, 2015
Several all-oral direct-acting antiviral (DAA) combination therapies including two fixed-dose combinations (FDCs) have been recently licensed for treatment of hepatitis C virus (HCV) genotype 1 infection. Results of pivotal trials with these new compounds are now also available in human immunodeficiency virus (HIV)/HCV-coinfected patients, highlighting
Christoph, Boesecke, Jürgen K, Rockstroh   +1 more
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HIV-1 genotypic and phenotypic resistance

Clinics in Laboratory Medicine, 2002
Antiretroviral failure caused by the development of drug resistance in HIV-1 is an increasingly common clinical problem. Two types of resistance assays are available to clinicians. Genotypic assays determine the presence of mutations associated with drug resistance.
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Genotypic subtypes of HIV-1 in Cameroon

AIDS, 1994
The only two HIV-1 strains (ANT70 and MVP5180) reported to date from Cameroon are members of the outlier clade (group O). In this study, we assessed the prevalence of group O viruses and other HIV-1 subtypes in Cameroon.A phylogenetic analysis of 18 HIV-1 strains isolated from seropositive individuals from Yaoundé and Douala, Cameroon.A 900 base-pair ...
Nkengasong, J. N., Janssens, W., Heyndrickx, L., Fransen, K., Ndumbe, P. M., Motte, J., Leonaers, A., Ngolle, M., Ayuk, J., Piot, P., van der Groen, G.   +10 more
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Two soybean genotypes lacking lipoxygenase‐1

Journal of the American Oil Chemists' Society, 1981
AbstractThe U.S. Department of Agriculture soybean germplasm collection (6,499 accessions) was screened for genotypes with greatly reduced or missing lipoxygenase‐1 (L‐1) [linoleate: O2 oxidoreductase, EC 1.13.11.12] and lipoxygenase‐2 and L‐3 (L‐2 and L‐3) activity.
D. F. Hildebrand, T. Hymowitz
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Genotype‐Phenotype Correlations in Type 1 Waardenburg Syndrome

The Laryngoscope, 1996
AbstractType 1 Waardenburg syndrome (WS1) is an autosomal dominant disorder characterized by dystopia canthorum, sensorineural deafness, and pigmentary disturbances. Previous work has linked the disease to PAX3, a transcription factor with two highly conserved DNA binding motifs: a paired box and a homeobox.
A K, Lalwani, A N, Mhatre, T B, San Agustin, E R, Wilcox   +3 more
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Genotypic analysis of HIV-1 coreceptor usage

2011
The acquired immunodeficiency syndrome (AIDS) is one of the biggest medical challenges in the world today. Its causative pathogen, the human immunodeficiency virus (HIV), is responsible for millions of deaths per year. Although about two dozen antiviral drugs are currently available, progression of the disease can only be delayed but patients cannot be
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HIV-1 resistance genotyping on dried serum spots

AIDS, 2005
To assess the feasibility of HIV-1 group M resistance genotyping on dried serum spots, by testing samples from previously untreated patients, patients on treatment, and patients having stopped treatment, representing a wide genetic diversity panel.Serum samples from 62 HIV-1-infected Caucasian and African patients, with viral load values from 715 ...
Jean-Christophe, Plantier, Raoudha, Dachraoui, Véronique, Lemée, Marie, Gueudin, Françoise, Borsa-Lebas, François, Caron, François, Simon   +6 more
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Neuregulin-1 genotypes and eye movements in schizophrenia

European Archives of Psychiatry and Clinical Neuroscience, 2009
Neuregulin-1 (NRG-1) is a putative susceptibility gene for schizophrenia but the neurocognitive processes that may involve NRG-1 in schizophrenia are unknown. Deficits in antisaccade (AS) and smooth pursuit eye movements (SPEM) are promising endophenotypes, which may be associated with brain dysfunctions underlying the pathophysiology of schizophrenia.
Haraldsson, H.M., Ettinger, U., Magnusdottir, B.B., Ingason, A., Hutton, S.B., Sigmundsson, T., Sigurdsson, E., Petursson, H.   +7 more
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