Results 121 to 130 of about 1,197,745 (340)
Noise in Genotype Selection Model
, 2003 We study the steady state properties of a genotype selection model in presence of correlated Gaussian white noise. The effect of the noise on the genotype selection model is discussed.
Ai, Bao-Quan +5 more
core +1 more source
A CASE OF IMPORT OF GENOTYPE 4 HEPATITIS E VIRUS INTO RUSSIA
Journal of microbiology, epidemiology and immunobiology, 2016 Aim. Description of the first documented case of imported hepatitis E, associated with genotype 4 of HEV and introduced from southern France. Materials and methods. Clinical, epidemiologic and laboratory analysis of the imported case of disease of hepatitis E was carried out.
M. I. Mikhailov +3 more
openaire +4 more sources
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Hepatitis C virus genotype 4 therapy: progress and challenges [PDF]
Liver International, 2011 AbstractThe hepatitis C virus genotype 4 (HCV‐4) is prevalent in Egypt, the Middle East and Africa. Recently, the epidemiology of HCV‐4 has changed and this genotype has begun to cross borders and spread to several regions in Europe through immigration and injection drug use.
openaire +2 more sources
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
The evolutionary dynamics of DENV 4 genotype I over a 60-year period.
PLoS Neglected Tropical Diseases, 2019 Dengue virus serotype 4 (DENV 4) has had a relatively low prevalence worldwide for decades; however, likely due to data paucity, no study has investigated the epidemiology and evolutionary dynamics of DENV 4 genotype I (DENV 4-I).
Shaowei Sang +6 more
doaj +1 more source
Virology Journal, 2012 Background Four major genotypes of hepatitis E virus (HEV), the causative agent of hepatitis E, have so far been recognized. While genotypes 3 and 4 are both zoonotic, the disease symptoms caused by the latter tend to be more severe.
Zhu Yumin +7 more
doaj +1 more source
Effects of neutral selection on the evolution of molecular species
, 1997 We introduce a new model of evolution on a fitness landscape possessing a tunable degree of neutrality. The model allows us to study the general properties of molecular species undergoing neutral evolution.
Engelhardt, Robin, Newman, M. E. J.
core +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Platelet protease-activated receptor 4 genotype and response to aspirin in pregnancy
Blood Vessels, Thrombosis & Hemostasis: The platelet protease-activated receptor 4 (PAR4) threonine 120 (Thr120) allele is an activating allele associated with reduced aspirin response in vitro. Aspirin is recommended in high-risk pregnancies to prevent preeclampsia and preterm birth.
Rupsa C. Boelig +6 more
doaj +1 more source