Results 131 to 140 of about 1,197,745 (340)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Quantification of host proteomic responses to genotype 4 hepatitis E virus replication facilitated by pregnancy serum. [PDF]

Virol J, 2023
Qian Z, Cong C, Li Y, Bi Y, He Q, Li T, Xia Y, Xu L, Mickael HK, Yu W, Liu J, Wei D, Huang F.   +12 more
europepmc   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Increased α-Fetoprotein Predicts Steatosis among Patients with Chronic Hepatitis C Genotype 4

International Journal of Hepatology, 2012
Background. The prognostic importance of α-fetoprotein (AFP) level elevation in patients with chronic hepatitis C and its clinical significance in steatosis associated with HCV infection remain to be determined.
Nasser Mousa, Yahia Gad, Azza Abdel-Aziz, Ibrahem Abd-Elaal   +3 more
doaj   +1 more source

A novel candidate hepatitis C virus genotype 4 subtype identified by next generation sequencing full-genome characterization in a patient from Saudi Arabia. [PDF]

Front Microbiol, 2023
Di Stefano M, Ismail MH, Leitner T, Faleo G, Alwazzeh MJ, Mbisa JL, Fiore JR, Santantonio TA.   +7 more
europepmc   +1 more source

Heterogeneity and New Epitopes of Hepatitis C Virus Genotype 4 [PDF]

, 2013
Moataza H Omran, Wael Nabil, Samar Samir Youssef, Mervat El-Sayed, Mostafa K. El Awady   +4 more
openalex   +1 more source

Evaluation of Resistance of Banana Genotypes with AAB Genome to Fusarium Wilt Tropical Race 4 in China [PDF]

, 2022
Ni Zhan, Mengyu Kuang, Weidi He, Guiming Deng, Siwen Liu, Chunyu Li, Nicolas Roux, Miguel Dita, Ganjun Yi, Ou Sheng   +9 more
openalex   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

HCV genotype 4 subtypes in people who inject drugs in sub-Saharan Africa. [PDF]

Lancet Gastroenterol Hepatol, 2022
Akiyama MJ, Nyakowa M, Riback LR, Cherutich P, Kurth AE.   +4 more
europepmc   +1 more source

Significance of mutations in the region coding for NS3/4 protease in patients infected with HCV genotype 1b. [PDF]

, 2018
Tadeusz Wojciech Łapiński, Magdalena Rogalska, Oksana Kowalczuk, Joanna Kiśluk, Joanna Zurnowska, Jacek Nikliński, Robert Flisiak   +6 more
openalex   +1 more source