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Current Management of Patients with HCV Genotype 4
2021Around 70 million people are chronically infected with HCV worldwide. HCV anti-viral drug development has been remarkable, and this revolution led to several direct-acting antiviral agents achieving an HCV cure after only 8–12 weeks of treatment duration. Epidemiological data had showed increasing prevalence of HCV genotype 4 worldwide.
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Elbasvir and grazoprevir for chronic hepatitis C genotypes 1 and 4
Expert Review of Clinical Pharmacology, 2016During the last few years, treatment of hepatitis C virus (HCV) revolutionized with the appearance of direct antiviral agents especially for patients with HCV genotypes 1 and 4 infections. Elbasvir (NS5A inhibitor) and grazoprevir (NS3/4A protease inhibitor) are newly developed drugs that are presented in fixed dose combination tablets.
Mohamed, El Kassas +3 more
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[The molecular differences between genotype 1 and genotype 4 of HEV in their neutralization region].
Bing du xue bao = Chinese journal of virology, 2008HEV is classified into H (human) group and Z (zoonosis) group according to its compatible host. H group contains genotype 1 and genotype 2 HEV isolates which infect human only; Z group contains genotype 3 and genotype 4 HEV isolates which infect both human and animals.
Qing-Shun, Guo +9 more
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Treatment of Chronic Hepatitis C, Genotype 4
Current Hepatitis Reports, 2013HCV-genotype 4 is the predominant genotype in patients in North-East (especially in Egypt and Lybia) and Sub-Saharan Africa and in most Middle Eastern countries and is spread by migration and IVDU to Europe in the last years. Current treatment consists of peginterferon-alfa2 plus ribavirin (Peg/RBV) combination therapy using a response guided approach ...
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Pangenotypic and genotype-specific antivirals in the treatment of genotype 4 infected patients with HIV coinfection [PDF]
Journal of Hepatology, 2022 Zarębska-Michaluk, Dorota +17 more
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Genotype and Cardiac Outcomes in Pediatric Dilated Cardiomyopathy
Journal of the American Heart Association, 2022Lisa Castillo +2 more
exaly
Ledipasvir–sofosbuvir for hepatitis C genotype 4 infection
The Lancet Infectious Diseases, 2015Michael A, Smith, Rima A, Mohammad
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Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes
Nature Methods, 2020Haynes Heaton +2 more
exaly