Asian genotypes of dengue virus 4 in Brazil
Epidemiology and Infection, 2015 SUMMARYDengue virus, commonly transmitted by mosquitoes, causes a human disease of significant social impact and presents a serious public health problem in Brazil. This report describes the unusual emergence of DENV-4 in northern Brazil after a nearly 30-year-long absence.
A C O, Pinho +6 more
openaire +2 more sources
Interferon lambda 4 genotype and pathway in alcoholic hepatitis
Scandinavian Journal of Gastroenterology, 2021 Single nucleotide polymorphisms within the interferon lambda 4 (IFNL4) gene influence liver inflammation and fibrosis in chronic liver disease. We investigated whether this is also the case during acute liver disease, alcoholic hepatitis. We, therefore, related variants within the IFNL4 gene to the clinical course of acute alcoholic hepatitis, and ...
Sidsel Støy (286606) +7 more
openaire +4 more sources
Development of a Method for Screening and Genotyping of HCV 1a, 1b, 2, 3, 4, and 6 Genotypes [PDF]
ACS Omega, 2020 The World Health Organization and the World Health Assembly recommended eradicating hepatitis as a public threat by 2030. The accurate genotyping of hepatitis C virus (HCV) is crucial to achieving this goal because it is vital for the selection of anti-HCV therapy required for complete cure of HCV infection.
Shrikant Dashrath Warkad +3 more
openaire +3 more sources
Grain Characteristics, Chemical Composition, and Functional Properties of Rye (Secale cereale L.) As Influenced by Genotype and Harvest Year [PDF]
, 2004 Grain characteristic, chemical composition, and functional properties of rye were measured in 19 different cultivars grown in one location in up to 3 years.
Andersen, S.B. +4 more
core +1 more source
The Iraqi Journal of Agricultural science, 2022 CTLA4 is well known that it is expressed in activated T-lymphocyte, and can be distinguished in cancer phenomena as well as many chronic diseases. This study was designed aiming to find a correlation between CTLA-4 and Rheumatoid Arthritis (RA).
Rawaa A. A.
doaj +1 more source
Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates [PDF]
, 2005 The majority of the keratitis-causing Acanthamoeba isolates are genotype T4. In an attempt to determine whether predominance of T4 isolates in Acanthamoeba keratitis is due to greater virulence or greater prevalence of this genotype, Acanthamoeba ...
Alsam +21 more
core +1 more source
How to optimize HCV therapy in genotype 4 patients [PDF]
Liver International, 2013 AbstractHCV is a worldwide disease with an estimated prevalence by WHO of 3%. Hepatitis C virus 4 is prevalent in Africa and the Middle East, especially Egypt. The treatment of HCV4 is affected by many factors, related to the virus itself (genotype, pretreatment viral load and prevalent quasispecies), to the host (genetic factors, age, ethnicity and ...
Gamal, Esmat +4 more
openaire +2 more sources
Rotavirus genetic diversity, disease association, and temporal change in hospitalized rural Kenyan children [PDF]
, 2010 Background. The effectiveness of rotavirus vaccines will be dependent on the immunity conferred against prevalent and emergent variants causing severe diarrheal disease.
Abwao, John +8 more
core +4 more sources
Treatment Options for HCV Genotype-4
Journal of Infectious Diseases & Therapy, 2016 For the last three decades, HCV infection had been a challenging health problem due to high prevalence rate, fatal complications and till recently the lack of effective treatment. In the pre directly acting agents (DAAs) era, the interferon-ribavirin based treatment was of limited success in the clearance of the virus compounded by major side effects ...
Albenmousa A, Al Obary E
openaire +1 more source
Baseline anti-NS4a antibodies in combination with on-treatment quantitative HCV-RNA reliably identifies nonresponders to pegylated interferon-ribavirin combination therapy after 4 weeks of treatment [PDF]
, 2010 Background Early detection of nonresponders to hepatitis C therapy limits unnecessary exposure to treatment and its side-effects. A recent algorithm combining baseline anti-NS4a antibodies and on-treatment quantitative PCR identified nonresponders to a ...
de Knegt, Robert J +8 more
core +1 more source