Results 41 to 50 of about 1,197,745 (340)

Genotypes and subtypes of hepatitis C virus in Burundi: a particularity in Sub-saharan Africa

The Pan African Medical Journal, 2014
INTRODUCTION: Hepatitis C virus (HCV) infection is a major public health issue. HCV genotype identification is clinically important to tailor the dosage and duration of treatment. Indeed, distinct therapeutic approaches are required for each genotype. Up
Rénovat Ntagirabiri, Jean Dominique Poveda, Annie Mumana, Hermelance Ndayishimiye   +3 more
doaj   +1 more source

Study of non-organ-specific antibodies in children with Genotype 4 chronic Hepatitis C

The Saudi Journal of Gastroenterology, 2013
Background/Aim: Adult studies established a relationship between hepatitis C virus (HCV) infection and the presence of non-organ-specific antibodies (NOSAs). Most studies were carried out on genotypes 1 and 2.
Mohammed E Hamed, Naglaa M Kamal Alanani, Laila M Sherief, Mohammed A Fouad, Lamiaa A Elwahab, Nermin Raafat   +5 more
doaj   +1 more source

Associations between BMI and the FTO Gene Are Age Dependent: Results from the GINI and LISA Birth Cohort Studies up to Age 6 Years [PDF]

, 2010
Objective: The association between polymorphisms in intron 1 of the fat mass and obesity associated gene (FTO) and obesity-related traits is one of the most robust associations reported for complex traits and is established both in adults and children ...
Bauer, Carl Peter, Berdel, Dietrich, Berg, Andrea von, Borte, Michael, Grallert, Harald, Hebebrand, Johannes, Heinrich, Joachim, Herbarth, Olf, Illig, Thomas, Koletzko, Sibylle, Krämer, Ursula, Rzehak, Peter, Sausenthaler, Stefanie, Schaaf, Beate, Scherag, Andre, Wichmann, Heinz-Erich   +15 more
core   +1 more source

Treatment efficacy of ledipasvir/sofosbuvir for 8 weeks in non-cirrhotic chronic hepatitis C genotype 4 patients

The Saudi Journal of Gastroenterology, 2019
Background/Aims: Ledipasvir/sofosbuvir (LDV/SOF) combination is administered for 12 to 24 weeks to treat hepatitis C virus (HCV); guidelines recommend 8 weeks treatment duration for HCV genotype (GT) 1 infection based on the patient's baseline ...
Mohammed A Babatin, Abdullah S AlGhamdi, Abdullah M Assiri, Haziz AlBiladi, Hammad S AlOthmani, Mohammed H Mogharbel, Wedad Mahallawi, Tarik Asselah, Faisal M Sanai   +8 more
doaj   +1 more source

Association between IL-4 genotype and IL-4 production in the Japanese population [PDF]

Genes & Immunity, 2002
We have identified that there are only two IL-4 gene haplotypes (I and II) in the Japanese population. There are significant differences among three genotypes (I/I, I/II and II/II) in the IL-4 producing proportion of peripheral Th cells using intracellular cytokine detection assay.
H, Nakashima, K, Miyake, Y, Inoue, S, Shimizu, M, Akahoshi, Y, Tanaka, T, Otsuka, M, Harada   +7 more
openaire   +2 more sources

Examination of the Monoamine Oxidase A Gene Promoter on Motivation to Exercise and Levels of Voluntary Physical Activity [PDF]

, 2017
Purpose: The purpose of this study was to examine the genetic basis underlying voluntary exercise. Monoamine oxidase A (MAO-A) is an enzyme that acts on monoamine neurotransmitters, such as dopamine, to cause inactivation. There are several polymorphisms
Kinney, Erin M.
core   +4 more sources

Efficacy and Safety of Ombitasvir, Paritaprevir and Ritonavir plus Ribavirin in Hepatitis C Genotype-4 Patients on Hemodialysis

Archives of Pharmaceutical Sciences Ain Shams University, 2020
Background: The ongoing standard treatment for patients with chronic hepatitis C virus (HCV) is a mixture of direct-acting antiviral agents (DAAs). Aim of work: the aim of this study is to analyse the efficacy and safety of oral interferon-free regimen ...
Mai Abdelmen , Nagwa Ali Sabri, Sara Shahin, Ashraf Ahmed Aboubakr   +3 more
doaj  

Neutropenia and viral load decline during treatment of hepatitis C virus genotype-4

The Turkish Journal of Gastroenterology, 2014
Background/Aims: Neutrophil count and magnitude of decrease from baseline are not correlated with infection rate in recipients of interferon-based therapy for hepatitis C (HCV).
Aliaa Amer, Fatma Shebl, Moutaz Derbala
doaj   +1 more source

The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis. [PDF]

, 2015
A previous study showed that, in carriers of the apolipoprotein E (APOE) genotype ε3/ε3 or ε3/ε4, the presence of a very long (VL) polyT repeat allele in "translocase of outer mitochondrial membrane 40" (TOMM40) was less frequent in patients with ...
Barohn, R.J., Bettencourt, C., Brady, S., De Bleecker, J., De Paepe, B., Dimachkie, M.M., Fox, Z., Gang, Q., Hanna, M.G., Healy, E., Hilton-Jones, D., Holton, J.L., Houlden, H., Machado, P.M., Mantegazza, R., Mastaglia, F., Moggio, M., Mora, M., Needham, M., Parton, M., Ripolone, M., Shaibani, A., Shieh, P.B., Violano, R., Zanoteli, E., Zanotti, S.   +25 more
core   +1 more source

Genotype 4 and the global challenge of hepatitis C treatment

The Lancet Gastroenterology & Hepatology, 2016
The therapeutic revolution in therapy for hepatitis C (HCV) seen in recent years has left some critical gaps with genotypes other than 1 have either lesser evidence of efficacy or proven lower efficacy. Even with the potential availability of drugs with cure rates approaching 100% it is uncertain how many populations across the world will have the ...
Ryder, S, Pett, S, Cooke, GS
openaire   +3 more sources