Results 41 to 50 of about 863,797 (309)

Genotypes

, 2011
Genotypes for all the individuals at the 12 loci used in the ...
Renaud Kaeuffer (448673), Andrew P. Hendry (235207), Catherine Lynn Peichel (3257421), Peichel, Catherine Lynn, Hendry, Andrew P., Kaeuffer, Renaud, Daniel I. Bolnick (37344), Bolnick, Daniel I.   +7 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

HPV genotypes in invasive cervical cancer: prevalence, risk attribution, and optimized vaccine strategies in western China

Frontiers in Public Health
BackgroundUnderstanding the HPV genotype distribution in invasive cervical cancer (ICC) is essential for vaccine optimization. This study presents a comprehensive analysis of HPV genotypes in ICC tissues from patients in western China, with the aim of ...
Yuling Kou, Yuling Kou, Xiao Tang, Xiao Tang, Dongni Liang, Dongni Liang, Chuan Xie, Chuan Xie, Jing Zeng, Jing Zeng, Meng Chen, Meng Chen, Wenjing Fu, Wenjing Fu, Zhonghua Li, Zhonghua Li, Qingfeng He, Tianming Liu, Tianming Liu, Mei Wang, Mei Wang, Wei Wang, Wei Wang, Cheng Wang, Cheng Wang   +24 more
doaj   +1 more source

Genotypes of Cryptosporidium Species Infecting Fur-Bearing Mammals Differ from Those of Species Infecting Humans [PDF]

, 2004
Of 471 specimens examined from foxes, raccoons, muskrats, otters, and beavers living in wetlands adjacent to the Chesapeake Bay, 36 were positive for five types of Cryptosporidium, including the C.
Schaefer, F.W., U. M. Ryan, Fayer, R., R. Fayer, L. Zhou, J. M. Trout, L. Xiao, Xiao, L., Ryan, U., Zhou, L., Trout, J.M., F. W. Schaefer   +11 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Imputation of genotypes from low- to high-density genotyping platforms and implications for genomic selection [PDF]

, 2011
peer-reviewedThe objective of this study was to quantify the accuracy achievable from imputing genotypes from a commercially available low-density marker panel (2730 single nucleotide polymorphisms (SNPs) following edits) to a commercially available ...
J.F. Kearney, Kearney, J.F., D.P. Berry, Berry, Donagh   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Current epidemiological, molecular and genetic characteristics of enteric viral hepatitis in Russia

Alʹmanah Kliničeskoj Mediciny, 2018
Rationale: Enteric hepatitis including hepatitis A and hepatitis E are globally prevalent diseases with large social and economic burden. In some patient categories these may be lethal.
E. V. Esaulenko, A. A. Sukhoruk, A. D. Bushmanova, T. Ingabire, Yu. V. Ostankova   +4 more
doaj   +1 more source

Priors for Genotyping Polyploids [PDF]

Bioinformatics, 2019
Abstract Motivation Empirical Bayes techniques to genotype polyploid organisms usually either (i) assume technical artifacts are known a priori or (ii) estimate technical artifacts simultaneously with the prior genotype distribution.
Gerard, David, Ferrão, Luís Felipe Ventorim   +1 more
openaire   +2 more sources

Taylor&Hoffman2-Genotypes-afterNullAlleles_Genepop

, 2013
Taylor&Hoffman2-Genotypes ...
Zachary Taylor (3319626), Hoffman, Susan, Susan Hoffman (3319623), Taylor, Zachary   +3 more
core   +1 more source