Results 61 to 70 of about 767,691 (307)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

perrier-genotypes-parus-major [PDF]

open access: yes, 2017
VCF file containing genotypes of the Parus major individuals. Individual names can be matched with the names found in the individuals.txt file in order to extract site of origin, coordinates, and urbanization ...
Arnaud Gregoire (3267345)   +5 more
core   +1 more source

Steatosis in chronic hepatitis B: Prevalence and correlation with biochemical, histologic, viral, and metabolic parameters

open access: yesIndian Journal of Pathology and Microbiology, 2011
Background and Aims: Hepatic steatosis (HS) is highly prevalent in chronic hepatitis C and is an important variable predicting progression of histological injury, insulin resistance, and reduced response to antiviral therapy. There are limited data on HS
Archana Rastogi   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Giardia genotypes in pigs in Western Australia: Prevalence and association with diarrhea [PDF]

open access: yes, 2009
Little is known of the prevalence of Giardia species and genotypes in pre- and post-weaned domestic pigs. In the present study, a total of 297 pig faecal samples were screened for the presence of Giardia by PCR and genotyped.
Armson, Anthony   +11 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Scofield-et-al_AmNat_52938_Quercus-agrifolia_pericarp-genotypes [PDF]

open access: yes, 2012
Genotypes of Quercus agrifolia collected from Acorn Woodpecker granaries at Sedgwick Reserve, Santa Barbara County, California, in 2006. Data are in GenAlEx format and represent diploid microsatellite genotypes.
Douglas G. Scofield (3311949)   +7 more
core   +1 more source

Comparative Morphological Evaluation of Different Chilli (Capsicum annuum L.) Varieties of Andhra Pradesh, India for Agronomic Traits [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2019
In the present study, 20 chilli cultivars were characterized based on morphology as it serves as discrete identification indicator and also propose to evaluate cultivar diversity for yield related parameters.
Naganirmala Kumari Bantu   +1 more
doaj  

Selection of open pollination progenies in some pear species in order to achieve dwarf and drought tolerant rootstocks

open access: yesAdvances in Horticultural Science, 2019
One of the important products in Iran and Isfahan province is the pear that its cultivation has been limited by drought stress and global warming in recent years.
Maryam Tatari   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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