Results 61 to 70 of about 863,797 (309)

Selection of open pollination progenies in some pear species in order to achieve dwarf and drought tolerant rootstocks

open access: yesAdvances in Horticultural Science, 2019
One of the important products in Iran and Isfahan province is the pear that its cultivation has been limited by drought stress and global warming in recent years.
Maryam Tatari   +3 more
doaj   +1 more source

Genotyping with TaqMAMA

open access: yesGenomics, 2004
TaqMAMA combines the quantitative strengths of TaqMan with the allele-specific PCR of MAMA. In this article we develop TaqMAMA as a technique for screening human DNA samples for known genetic polymorphisms. In the first set of experiments, plasmids that model all types of genetic polymorphisms were used to understand the relationship between TaqMAMA ...
Baohui, Li   +3 more
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Occult Hepatitis B Virus Infection in Chacma Baboons, South Africa

open access: yesEmerging Infectious Diseases, 2013
During previous studies of susceptibility to hepatitis B virus (HBV) infection, HBV DNA was detected in 2/6 wild-caught baboons. In the present study, HBV DNA was amplified from 15/69 wild-caught baboons. All animals were negative for HBV surface antigen
Caroline Dickens   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Immunomodulatory Function of HBeAg Related to Short-Sighted Evolution, Transmissibility, and Clinical Manifestation of Hepatitis B Virus

open access: yesFrontiers in Microbiology, 2018
Hepatitis B virus (HBV) infection, a global public health problem can be asymptomatic, acute or chronic and can lead to serious consequences of infection, including cirrhosis, and hepatocellular carcinoma.
Anna Kramvis   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Dabie bandavirus identified from patients with severe fever with thrombocytopenia syndrome in northwestern of Hubei Province, China, 2024

open access: yesFrontiers in Public Health
IntroductionSevere fever with thrombocytopenia syndrome (SFTS), caused by Dabie bandavirus (DBV), is a zoonotic disease characterized by substantial mortality. Hubei Province is an epidemic region with a high incidence rate of SFTS.
Mengzhu Zhang   +15 more
doaj   +1 more source

Genotypes

open access: yes, 2012
This file contains genotypes at 10 microsatellite loci for Chinook salmon collected in the fish passage facility at Landsburg Diversion Dam, Cedar River, WA, USA.
Quinn, Thomas P.   +7 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy