Results 81 to 90 of about 767,691 (307)

imputed-seq-genotypes-Chr3.15020000-16020000.vcf [PDF]

, 2017
Imputed genotypes for variants within 1Mbp of the Chr3:15.52 LC QTL, for 357 ...
Thomas Lopdell (511314), Thomas Johnson (363281), Russell Snell (387740), Christine Couldrey (169434), Maksim Struchalin (166855), Ric Sherlock (511317), Mathew Littlejohn (4690033), Steve Davis (5017841), Kathryn Tiplady (511313), Richard Spelman (387738), Michael Keehan (4690036)   +10 more
core   +1 more source

The Role of MHC-II Diversity over Enclosure Design in Gut Microbiota Structuring of Captive Bengal Slow Lorises

Biology
The endangered Bengal slow loris (Nycticebus bengalensis) relies heavily on captive/rescue populations for conservation. This study investigated the critical link between Major Histocompatibility Complex (MHC) class II DRB1 exon 2 (DRB1e2) genetic ...
Rong Jiang, Xiaojia Zhang, Lei Xie, Yan Zhang, Changjun Zeng, Yongfang Yao, Huailiang Xu, Caoyang Yang, Xiao Wang, Qingyong Ni, Meng Xie, Chuanren Li   +11 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

imputed-seq-genotypes-12k-Chr19.60630000-61630000.vcf [PDF]

, 2017
Imputed genotypes for variants within 1Mbp of the Chr19:61.13 LC QTL, for 12,000 ...
Thomas Lopdell (511314), Thomas Johnson (363281), Russell Snell (387740), Christine Couldrey (169434), Maksim Struchalin (166855), Ric Sherlock (511317), Mathew Littlejohn (4690033), Steve Davis (5017841), Kathryn Tiplady (511313), Richard Spelman (387738), Michael Keehan (4690036)   +10 more
core   +1 more source

Genotypic variations of Porphyromonas gingivalis in chronic periodontitis patients with and without diabetes: An in vitro study using arbitrarily primed-polymerase chain reaction and heteroduplex-polymerase chain reaction

Journal of Indian Society of Periodontology, 2019
Context: Diabetes has become an endemic throughout the world. Periodontitis is associated with diabetes, and it has been regarded as the sixth complication of diabetes.
Siladitya Sen, Kukkamalla Meena Anand
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

imputed-seq-genotypes-Chr19.60630000-61630000.vcf [PDF]

, 2017
Imputed genotypes for variants within 1Mbp of the Chr19:61.13 LC QTL, for 357 ...
Thomas Lopdell (511314), Thomas Johnson (363281), Russell Snell (387740), Christine Couldrey (169434), Maksim Struchalin (166855), Ric Sherlock (511317), Mathew Littlejohn (4690033), Steve Davis (5017841), Kathryn Tiplady (511313), Richard Spelman (387738), Michael Keehan (4690036)   +10 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

imputed-seq-genotypes-12k-Chr20.57950000-58950000.vcf [PDF]

, 2017
Imputed genotypes for variants within 1Mbp of the Chr20:58.45 LC QTL, for 12,000 ...
Thomas Lopdell (511314), Thomas Johnson (363281), Russell Snell (387740), Christine Couldrey (169434), Maksim Struchalin (166855), Ric Sherlock (511317), Mathew Littlejohn (4690033), Steve Davis (5017841), Kathryn Tiplady (511313), Richard Spelman (387738), Michael Keehan (4690036)   +10 more
core   +1 more source

Human Papillomavirus Genotype Distribution in Penile Cancer: Clinical, Histopathological, Radiological Correlations, and Public Health Perspectives

Indian Journal of Public Health
Human papillomavirus (HPV) appears to play an important role in the development of penile cancer. Research indicates geographical variations in HPV prevalence in penile cancer.
Bulbul Roy, Ajanta Sharma, Gitika Rajbongshi, Kailash Chamuah, Sasanka Baruah   +4 more
doaj   +1 more source