Results 71 to 80 of about 863,797 (309)

The Role of MHC-II Diversity over Enclosure Design in Gut Microbiota Structuring of Captive Bengal Slow Lorises

open access: yesBiology
The endangered Bengal slow loris (Nycticebus bengalensis) relies heavily on captive/rescue populations for conservation. This study investigated the critical link between Major Histocompatibility Complex (MHC) class II DRB1 exon 2 (DRB1e2) genetic ...
Rong Jiang   +11 more
doaj   +1 more source

RSBL-2013-0125-Genotypes

open access: yes, 2013
Genotypes of Pachycondyla inversa workers and queens on 5 microsatellite ...
Heikki Helanterä (486202)   +4 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Genotypic variations of Porphyromonas gingivalis in chronic periodontitis patients with and without diabetes: An in vitro study using arbitrarily primed-polymerase chain reaction and heteroduplex-polymerase chain reaction

open access: yesJournal of Indian Society of Periodontology, 2019
Context: Diabetes has become an endemic throughout the world. Periodontitis is associated with diabetes, and it has been regarded as the sixth complication of diabetes.
Siladitya Sen, Kukkamalla Meena Anand
doaj   +1 more source

validation-genotypes-lc.vcf

open access: yes, 2017
Genotypes of the 22 tag SNPs for the LC phenotype QLT peaks in the 18k validation ...
Thomas Lopdell (511314)   +21 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

SNP Genotyping and ApoE Genotyping v1

open access: yes, 2021
This protocol details the steps for DNA extraction from a human blood sample, quality control, and SNP and APOE genotyping. The protocol has been adapted from the PRoBaND SNP Genotyping and ApoE Genotyping Protocol. The overall protocol for PRoBaND /Tracking Parkinson’s is published: Malek, N., Swallow, D. M. A., Grosset, K. A., Lawton, M.
Huw Morris   +3 more
openaire   +1 more source

validation-genotypes-ly.vcf

open access: yes, 2017
Genotypes of the 5 tag SNPs for the LY phenotype QLT peaks in the 18k validation ...
Thomas Lopdell (511314)   +21 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Human Papillomavirus Genotype Distribution in Penile Cancer: Clinical, Histopathological, Radiological Correlations, and Public Health Perspectives

open access: yesIndian Journal of Public Health
Human papillomavirus (HPV) appears to play an important role in the development of penile cancer. Research indicates geographical variations in HPV prevalence in penile cancer.
Bulbul Roy   +4 more
doaj   +1 more source

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