Results 111 to 120 of about 2,721,776 (301)

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Genotypic resistance profiles in Chinese patients with chronic hepatitis B virus infection and the efficacy of nucleoside analog rescue therapy

, 2015
Ling-Bo Liang, Lan-Lan Chen, En-Qiang Chen, Juan Liao, Hong Tang Center of Infectious Disease, State Key Laboratory of Biotherapy, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, People’s Republic of China ...
Liao J, Liang LB, Chen EQ, Chen LL, Tang H   +4 more
core  

Genotypic Clustering from Open Targets

<p>These data are from genotypic clustering from Open Targets.
Leyfer, Dmitriy, Narsingpurkar, Vallari, Mahendran, Jawahar   +2 more
core   +1 more source

Lack of correlation between constitutive and induced resistance to a herbivore in crucifer plants: real or flawed by experimental methods? [PDF]

, 2009
The correlation between constitutive and induced resistance to herbivores in plants has long been of interest to evolutionary biologists, and various approaches to determining levels of resistance have been used in this field of research.
Dicke, M., Liu, S.S., Zhang, P.J., Wu, Z.Y., Shu, J.P.   +4 more
core   +1 more source

Phenotypic characteristics of isolates of Aspergillus section Fumigati from different geographic origins and their relationships with genotypic characteristics

BMC Infectious Diseases, 2011
Background Epidemiological studies worldwide have shown that A. fumigatus exhibits important phenotypic and genotypic diversity, and these findings have been of great importance in improving the diagnosis and treatment of diseases caused by this fungus ...
del Rocío Reyes-Montes María, Buitrago María, López-Martínez Irma, Zepeda-Rodríguez Armando, Pérez-Torres Armando, Duarte-Escalante Esperanza, Córdoba Susana, Zúñiga Gerardo, Zavala-Ramírez Monserrat, Frías-De León María   +9 more
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Phenotypic and genotypic background underlying variations in fatty acid composition and sensory parameters in European bovine breeds

, 2014
Authors’ contributions: NS carried out the molecular genetic studies, performed the statistical analysis and drafted the manuscript. SD, HL, GN, CS, AV and JLW conceived the study, and participated in its design and coordination.
Nute, Geoffrey R., Williams, John L., Sañudo, Carlos, GemQual Consortium, Valentini, Alessio, Levéziel, Hubert, Sevane Fernández, Natalia, Dunner Boxberger, Helene Susana   +7 more
core   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Phenotypic and genotypic characteristics of small colony variants and their role in chronic infection [PDF]

, 2015
Small colony variant (SCV) bacteria arise spontaneously within apparently homogeneous microbial populations, largely in response to environmental stresses, such as antimicrobial treatment.
Tucker, Nicholas P., Maddocks, Sarah E., Purdy, Kevin J., Johns, Benjamin E.   +3 more
core   +2 more sources

GATA2 at 14: genotype-phenotype correlations

Haematologica
GATA2 mutations cause adult-onset bone-marrow failure characterized by cytopenias, infections and increased risk of myeloid malignancy. We reviewed hospital records and referrals of 232 GATA2 mutated individuals from 122 families to gather hematopoietic and syndromic features.
Amy P, Hsu, Subrata, Paul, Jennifer L, Kwan, Philip L F, Johnson, Justin, Lack, Eva P, Szymanski, Jana, Lovell, Ladan, Foruraghi, Cindy, Palmer, Christa S, Zerbe, Janine R, Daub, Joie, Davis, Dennis D, Hickstein, Katherine R, Calvo, Steven M, Holland   +14 more
openaire   +2 more sources