Results 141 to 150 of about 131,669 (291)

Phenotypic and Genotypic Characterization and Correlation Analysis of Pea (Pisum sativum L.) Diversity Panel [PDF]

, 2022
Ana Uhlarik, Marina Ćeran, Dalibor Živanov, Radu Grumeza, Leif Skøt, Ellen Sizer-Coverdale, David Lloyd   +6 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Genotypic interrelationships for flowering traits in sugarcane genotypes treated by Gibberellic acid under natural conditions

Journal of Sugarcane Research
The low flowering intensity of some sugarcane germplasm decreases seed yield. Flowering ability and intensity are desired traits for a successful sugarcane breeding program. The goal of the study  was to evaluate the effects of  various foliar gibberellic
Farrag F. B. Abu-Ellail, E.S.R. Salem, El-Sheikh A.M.   +2 more
doaj   +1 more source

Measuring Plant Genetic Diversity Using Inter-Simple Sequence Repeats (ISSRS) [PDF]

, 2007
Simple sequence repeats (SSRs) have great utility as they are conserved and present in all eukaryotic genomes. Here we report the use of a simple PCR with fluorescently-labelled primers to amplify inter-SSR markers (ISSRs) for diversity assessments.
Iannetta, Pietro
core  

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

Comparative asessment of bacterial excrection degree depending from sensivity profile of Mycobacterium tuberculosis to antituberculosis drugs

Annals of Mechnikov's Institute, 2019
One of the important part of the epidemiological component of tuberculosis pathomorphosis in modern conditions is the change in important biological properties of the pathogen, not only in the form of increased frequency and extension of Mycobacterium ...
O Schevchenko, O Hovardovska
doaj  

Genotypic Correlation of Biometric Traits and Leaf Curl Virus in Tomato [PDF]

, 2009
K. Sundharaiya, P. Jansirani, D. Veeraragavathatham, Muttucumaru Sivakumar   +3 more
openalex   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Potential traits for aiding selection for high grain yield based on trait association and path analysis in sorghum

Journal of Underutilised Crops Research
Background: Simultaneous breeding of grain yield and desirable agronomic traits are effective when the traits are positively correlated and heritability is high.
Miriam K. Chibvongodze, Edmore Gasura, Casper N. Kamutando, Stanford Mabasa, Brighton Makovere, Elijah Nyakudya, Ancilia Nhamo, Florence Mtambanengwe, Paul Mapfumo   +8 more
doaj   +1 more source

Phenotypic and genotypic correlation between myopia and intelligence. [PDF]

Sci Rep, 2017
Williams KM, Hysi PG, Yonova-Doing E, Mahroo OA, Snieder H, Hammond CJ.   +5 more
europepmc   +1 more source