Results 141 to 150 of about 63,568 (308)

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti   +5 more
wiley   +1 more source

Path analysis and expected response in indirect selection for grain yield in soybean

open access: yesCrop Breeding and Applied Biotechnology, 2006
This study aimed to determine the best auxiliary trait for indirect selection of soybean grain yield, through path analysis and in avoidance of the adverse effects of multicollinearity and expected response.
Ivana Marino B·rbaro   +5 more
doaj  

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Estimates of genetic variability and correlation coefficient for yield and its traits in black cumin (Nigella sativa L.) Genotypes in South Wollo Ethiopia

open access: yesAdvances in Horticultural Science
Black cumin (Nigella sativa L.) is a valuable annual spice used in food, cosmetics, and industrial products. However, productivity is limited by the lack of improved varieties, mainly due to insufficient knowledge of the genetic diversity within ...
Adem Endris Seid, Y. Gedamu
doaj   +1 more source

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

METHODS FOR KINO EVALUATION AND ESTIMATES OF GENETIC PARAMETERS IN Corymbia

open access: yesRevista Árvore
Species within the genus Corymbia are regarded as potential alternatives to Eucalyptus. In addition to having superior wood quality, Corymbia spp. are tolerant to most pests, diseases, and abiotic stresses that affecting Eucalyptus plantations, including
Michele Brandão Damacena   +7 more
doaj   +1 more source

Double‐Interpenetrating Composite Bioink for Multi‐Component 3D Bioprinting and Biofabrication

open access: yesAdvanced Functional Materials, EarlyView.
Marine‐polysaccharides‐derived double interpenetrating network hydrogel‐based bioink, combining the attributes of physical and ionic crosslinking, enables room‐temperature bioprinting of mechanically defined structures that can be handled and are cytocompatible.
Fabian Tribukait‐Riemenschneider   +1 more
wiley   +1 more source

Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems

open access: yesAdvanced Materials, EarlyView.
DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther   +9 more
wiley   +1 more source

Genotype‐Phenotype Correlations [PDF]

open access: yes, 2005
Julia E. Richards, R. Scott Hawley
openaire   +2 more sources

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

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