Results 51 to 60 of about 63,568 (308)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Using triple test cross analysis to estimate genetic components and genetic correlation for some quantitative traits in cotton [PDF]
Archives of Agriculture Sciences JournalThe triple test cross analysis was used to study different components of genetic variation between 75 Triple Test Cross (TTC) families and their parents, F1 and F2 in one cotton cross (Giza 94 × Australy) for yield, its components and fiber quality ...
A. Soliman +3 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Cogent Food & Agriculture, 2018 Identification of superior genotypes from variability generated via hybridization and understanding the nature of the gene action controlling grain yield and related traits are crucial for cowpea varietal improvement.
Emmanuel Yaw Owusu +4 more
doaj +1 more source
Determination of Agronomic Characteristics as Selection Criteria in Potato Crossing Lines
Planta Tropika: Jurnal Agrosains, 2022 Vegetative propagation of potato decreases variation in commercially cultivated varieties. Induction of variability in potatoes is needed for crop improvement.
Erny Ishartati +4 more
doaj +1 more source
Phenotype-Genotype Correlation in β-Thalassemia
Thalassemia Reports, 2011 The clinical manifestations of β-thalassemia are extremely heterogeneous, ranging from severe transfusion-dependent anemia, to the mild non transfusion dependent thalassemia intermedia and to the asymptomatic carrier state. The remarkable phenotypic variability is primary due to variations in the different globin genes (primary gene modifiers).
R. Galanello +4 more
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Correlation between genotypic (AMR-PCR assay) and phenotypic AST of E. coli isolates (N = 239).
, 2019 Correlation between genotypic (AMR-PCR assay) and phenotypic AST of E. coli isolates (N = 239).
Jean Gratz (412093) +17 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Bayesian estimation of genotypic and phenotypic correlations from crop variety trials [PDF]
, 2016 Genotypic and phenotypic correlations are necessary for constructing indirect selection indices. Bayesian analysis, therefore, was applied to obtain posterior distributions of the correlations, and the estimates were compared with those under a ...
Omer, Siraj Osman
core +3 more sources