Results 51 to 60 of about 2,721,776 (301)

Deciphering Pearl Millet Grain Yield under Water Stress using Genotypic, Phenotypic Correlation and Path Coefficient Analysis

open access: yes, 2022
Yield is a polygenic character, usually depends on its various contributing traits like days to 50% flowering, plant height, and panicle length as well as panicle girth.
Barupal, Heeralal   +5 more
core   +1 more source

Determination of Agronomic Characteristics as Selection Criteria in Potato Crossing Lines

open access: yesPlanta Tropika: Jurnal Agrosains, 2022
Vegetative propagation of potato decreases variation in commercially cultivated varieties. Induction of variability in potatoes is needed for crop improvement.
Erny Ishartati   +4 more
doaj   +1 more source

Genotype-phenotype correlations in tuberous sclerosis [PDF]

open access: yesJournal of Medical Genetics, 2000
Editor—Van Slegtenhorst et al 1 reported a mutational analysis of 225 patients with tuberous sclerosis (TSC) and concluded that there was no evidence for genotype-phenotype correlation. At virtually the same time, Jones et al 2 from Cardiff published supportive evidence for genotype-phenotypic correlation in their comprehensive mutational analysis of ...
P J, De Vries, P F, Bolton
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Correlation tests between phenotypic and genotypic patterns of clonal complexes’ resistance to ciprofloxacin, nalidixic acid, and tetracycline.

open access: yes, 2020
Correlation tests between phenotypic and genotypic patterns of clonal complexes’ resistance to ciprofloxacin, nalidixic acid, and tetracycline.
Mohamed Medhat Ali (8321238)   +6 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Study and evaluation of correlation techniques for automotive sensor data [PDF]

open access: yes, 2023
openI sistemi di guida completamente autonomi sono dotati di avanzati sensori in grado di rilevare e riconoscere rapidamente oggetti nell'ambiente circostante.
POZZEBON, MATTEO
core  

Phenotype-Genotype Correlation in β-Thalassemia

open access: yesThalassemia Reports, 2011
The clinical manifestations of β-thalassemia are extremely heterogeneous, ranging from severe transfusion-dependent anemia, to the mild non transfusion dependent thalassemia intermedia and to the asymptomatic carrier state. The remarkable phenotypic variability is primary due to variations in the different globin genes (primary gene modifiers).
Galanello, R.   +4 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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