Results 41 to 50 of about 58,360 (267)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source
Phenotype-Genotype Correlation in β-Thalassemia
Thalassemia Reports, 2011 The clinical manifestations of β-thalassemia are extremely heterogeneous, ranging from severe transfusion-dependent anemia, to the mild non transfusion dependent thalassemia intermedia and to the asymptomatic carrier state. The remarkable phenotypic variability is primary due to variations in the different globin genes (primary gene modifiers).
Galanello, R. +4 more
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Genetic gain in Passiflora seed traits from recurrent selection among full-sib families
Crop Breeding and Applied Biotechnology, 2023 The germination potential must be considered in the selection of passion fruit genotypes, since vigorous seeds originate seedlings with a higher growth rate, resulting in superior plants with high agronomic performance.
Rosenilda de Souza +4 more
doaj
Correlation studies for yield and its component traits in newly derived lines of kharif sorghum
Electronic Journal of Plant Breeding, 2017 Twenty six derived lines (named as AKENT number) along with resistant line (IS 18551), two susceptible lines (AKMS-14 B, DJ-6514) of kharif sorghum were evaluated for yield and yield components.
Ranjith P, R. B. Ghorade, V.V.Kalpande
doaj +1 more source
Electronic Journal of Plant Breeding, 2021 An experiment was carried out on fenugreek genotypes to study the genetic variability, and relationship among yield traits. Analysis of variance showed that the genotypes significantly differed in all the growth and yield parameters studied.
B. Krishnaveni1, P. Irene Vethamoni1*, B. Senthamizh Selvi1 and M. Raveendran2
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Cogent Food & Agriculture, 2018 Identification of superior genotypes from variability generated via hybridization and understanding the nature of the gene action controlling grain yield and related traits are crucial for cowpea varietal improvement.
Emmanuel Yaw Owusu +4 more
doaj +1 more source
Estimates of genetic parameters, genetic variability, and selection in the S1 generation of peach [PDF]
Ciência Rural: The growing of peach in mild winter regions is made viable through the use of genotypes that have low need for cold conditions, and this is one of the main aims of breeding for these regions.
José Osmar da Costa e Silva +5 more
doaj +2 more sources