Results 161 to 170 of about 493,667 (296)

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Impact of two field preservation methods on genotyping success of feces. [PDF]

PeerJ
Valencia-Montoya V, Salado I, Sanchez-Donoso I, Fernández-Gil A, Vilà C, Leonard JA.   +5 more
europepmc   +1 more source

The importance of genotype by environment interaction with reference to control populations [PDF]

, 1962
David F. Bray, A. E. Bell, Steven C. King   +2 more
openalex   +1 more source

UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis

Advanced Science, EarlyView.
These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang, Lilong Zhang, Beiying Deng, Wanrong Jiang, Tianrui Kuang, Chen Chen, Kailiang Zhao, Qiao Shi, Jun He, Weixing Wang   +9 more
wiley   +1 more source

The Establishment of a Sheep Embryo Genomic Selection System. [PDF]

Int J Mol Sci
Wang Y, Qin H, Li K, Hao J, Liu X, Chen D, Cheng L, He H, Wu R, Wu Y, Wang Y, Guo M, Li Q, An L, Tian J, Han H, Xi G.   +16 more
europepmc   +1 more source

Predictive genotype [PDF]

Canadian Medical Association Journal, 2010
Shinya, Ito, Bruce C, Carleton
openaire   +2 more sources

Genotype and Environment in Sire Evaluation

, 1963
L.D. Van Vleck
openalex   +1 more source

THE B BLOOD GROUP SYSTEM OF CHICKENS. II. THE EFFECTS OF GENOTYPE ON LIVABILITY AND EGG PRODUCTION IN SEVEN COMMERCIAL INBRED LINES [PDF]

, 1961
W. Elwood Briles, Courtney P. Allen
openalex   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

DNA polymerases in Biotechnology

Frontiers in Microbiology, 2014
Andrew F Gardner, Zvi eKelman
doaj   +1 more source